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The Human Upgrade: Biohacking for Longevity & Performance

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Dave Asprey

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

#1430

Feel 70 Percent Better… With Grapes? | Biohacking Tools : 1374

If you care about longevity, mitochondria, cardiovascular health, or feeling sharper every... more

10 hrs Ago

1 HR 01 MINS

1:01:16

10 hrs Ago

#1429

The Machine That Flicks on Your Brain in 30 Seconds | Biohacker Tools : 1373

This episode shows you how light, vibration, and frequency-based technology can shift your... more

02 Dec 2025

55 MINS

55:57

02 Dec 2025

#1428

How I Lost 100 Pounds By Drinking Butter Coffee : 1371

In 1999, a Silicon Valley millionaire on the brink of collapse took one mysterious sip ato... more

30 Nov 2025

22 MINS

22:36

30 Nov 2025

#1427

Get a Full Body Workout in 10 Minutes by Doing NOTHING | Biohacks : 1372

Most people think you need sweat, strain, or long workouts to upgrade circulation, metabol... more

28 Nov 2025

45 MINS

45:05

28 Nov 2025

#1426

These Secret Compounds Help Injuries Recover 2-3x Faster : 1370

Prepare to rethink surgery, healing, anesthesia, and recovery. This episode gives you a co... more

27 Nov 2025

1 HR 16 MINS

1:16:15

27 Nov 2025

#1425

Why Breathwork Feels Like a Euphoric Drug | Biohacker Tips : 1369

Breathwork is one of the most powerful tools in biohacking, yet most people only experienc... more

25 Nov 2025

51 MINS

51:10

25 Nov 2025

#1424

Dead Water Is Making You Sick! (Biohacking Bonus Episode) : 1368

Here’s the hidden story behind why you can chug “pure” water all day and still feel foggy,... more

24 Nov 2025

14 MINS

14:22

24 Nov 2025

#1423

10-Minute Biohacking News Update : 1367

This episode covers: •Nano CBD Pain Relief Without Cognitive Side Effects A new nano-micel... more

21 Nov 2025

09 MINS

09:45

21 Nov 2025

#1422

The Methylene Blue Episode | Solo Biohacking Masterclass : 1366

Methylene blue is one of the most misunderstood compounds in biohacking, yet it can upgrad... more

20 Nov 2025

35 MINS

35:37

20 Nov 2025

#1421

The Tiny Implant Replacing Life-Changing Drugs | Biohacking Tools : 1365

Bioelectronic medicine is changing how we treat inflammation, autoimmunity, and chronic di... more

18 Nov 2025

56 MINS

56:04

18 Nov 2025

#1420

The Boring Secret Behind Celebrities Who Don’t Age : 1364

What if the secret to living longer wasn't locked in a lab, but hiding in plain sight? And... more

16 Nov 2025

14 MINS

14:50

16 Nov 2025

#1419

Biohacking News Weekly Update : 1363

This episode covers: • Cocoa Extract Cuts Heart Deaths A massive COSMOS trial found that o... more

14 Nov 2025

10 MINS

10:00

14 Nov 2025

#1418

How to Build Muscle WITHOUT Lifting! Biohacker Longevity : 1362

Your workouts may be doing less than you think, and science now proves why. This episode r... more

13 Nov 2025

1 HR 03 MINS

1:03:49

13 Nov 2025

#1417

Why Motivation DOESN’T Work | Mental Biohacks : 1361

True transformationdoesn’tcome from motivation. It comes from rewiring your mind, reshapin... more

11 Nov 2025

39 MINS

39:28

11 Nov 2025

#1416

New Japanese Walking Hack Burns More Fat Than 10,000 Steps : 1360

Discover a little-known Japanese walking technique that outperforms 10,000 steps a day. It... more

09 Nov 2025

09 MINS

09:22

09 Nov 2025

#1415

Biohacking News Weekly Update : 1359

Upgradeyour biology in 10 minutes with this week’s rundown from Dave Asprey. This episode ... more

07 Nov 2025

11 MINS

11:39

07 Nov 2025

#1414

The Strange Science Behind Tylenol and Heartbreak | Daniel Amen : 1358

Painisn’tjust in yourbody,it’sin your brain. In this groundbreaking episode, Host Dave Asp... more

06 Nov 2025

1 HR 00 MINS

1:00:08

06 Nov 2025

#1413

The New SCIENCE of Energy Healing | Biohacking Updated : 1357

Your body does not just run on food or supplements. It runs on energy and information. Thi... more

04 Nov 2025

37 MINS

37:16

04 Nov 2025

#1412

Your Body Has an Anti-Aging Switch (Here’s How to Turn It On) : 1356

What if getting older had less to do with your birthday and more to do with the health of ... more

02 Nov 2025

21 MINS

21:52

02 Nov 2025

#1411

What Happens When You Live Inside a Quantum Field? (Anti-Aging Secrets) : 1355

Discover how quantum energy, frequency medicine, and consciousness science are rewriting w... more

31 Oct 2025

45 MINS

45:24

31 Oct 2025

#1410

Master Stress in 10 Seconds with THIS Heartbeat Technique : 1354

Heart rate variability isn’t just a fitness metric, it’s the master signal of human perfor... more

30 Oct 2025

1 HR 10 MINS

1:10:18

30 Oct 2025

#1409

Biohacking Cannabis: The DNA Science of Plant Medicine : 1353

Discover how decoding your DNA can unlock the full potential of plant medicine. This episo... more

28 Oct 2025

43 MINS

43:13

28 Oct 2025

#1408

This Legal Focus Powder Beats Any Dopamine Detox : 1352

Dopamine isn’t the enemy—low brain energy is. When your mitochondria can’t make enough ATP... more

26 Oct 2025

18 MINS

18:27

26 Oct 2025

#1407

Biohacking News Weekly Update : 1351

Upgrade your biology in 10 minutes with this week’s rundown from Dave Asprey. This episode... more

24 Oct 2025

05 MINS

05:57

24 Oct 2025

#1406

How Biohackers Use Nicotine WITHOUT Getting Addicted : 1350

This is Part 2 of the Nicotine Masterclass. If you haven’t heard Part 1, start there for a... more

23 Oct 2025

34 MINS

34:28

23 Oct 2025

#1405

Why Women’s Joints Are Failing 10x Faster : 1349

Modern joint pain isn’t just wear and tear—it’s a systemic, metabolic disease that starts ... more

21 Oct 2025

57 MINS

57:16

21 Oct 2025

#1404

Why You Still Feel Tired And Foggy On A Perfect Diet : 1348

Biohacking isn’t just food + exercise, it’s about fixing the invisible disruptors wrecking... more

19 Oct 2025

12 MINS

12:36

19 Oct 2025

#1403

10 Minute Weekly Biohacking Update : 1347

Upgrade your biology in 10 minutes with this week’s rundown from Dave Asprey. T This episo... more

17 Oct 2025

06 MINS

06:01