18-year-olds wake up fresh because their repair system still works. This episode shows you how stem cell decline quietly drives fatigue, inflammation, and faster aging, and how fasting can reactivate your body’s natural ability to repair itself without expensive stem cell procedures.&nbsp;Grab a generous 30% discount on any STEMREGEN product with:&nbsp;<a href="http://stemregen.co/dave30" rel="noopener noreferrer" target="_blank">http://stemregen.co/dave30</a>&nbsp;Dave Asprey sits down with Christian Drapeau, a neuroscientist trained at McGill University and a leading researcher in stem cell science. Christian pioneered a therapeutic approach called Endogenous Stem Cell Mobilization, authored the bestselling book Cracking the Stem Cell Code, and developed the concept of stem cell enhancement. He is the Founder and CSO of STEMREGEN, where his work focuses on helping the body release and use its own stem cells more effectively.&nbsp;Together, they break down why many injected stem cells never survive long enough to help, how the lungs trap&nbsp;a large percentage&nbsp;of IV stem cells, and why releasing your own stem cells into arterial circulation changes the outcome. They explore stem cell decline as a core driver of aging, tissue degeneration, and chronic inflammation, and explain why fasting is currently the only intervention shown to rejuvenate stem cells through autophagy.&nbsp;You’ll&nbsp;hear why a three-day fast has measurable effects on bone marrow aging, how stem cells act as signaling molecules that coordinate repair across the body, and why mitochondria play a massive and underappreciated role in stem cell renewal and tissue regeneration. The conversation also covers scar tissue, fibrosis, recovery from injury, and why healing quality matters just as much as healing speed.&nbsp;You’ll&nbsp;Learn:&nbsp;• Why stem cell decline, not simple wear and tear, drives aging&nbsp;• How fasting supports stem cell rejuvenation through autophagy&nbsp;• Why many injected stem cells die in the lungs before helping tissue&nbsp;• How releasing your own stem cells differs from IV stem cell therapy&nbsp;• Why mitochondria are central to stem cell function and repair&nbsp;• How scar tissue and fibrosis form when repair fails&nbsp;• Why recovery quality&nbsp;determines&nbsp;long-term resilience and longevity&nbsp;Dave Asprey is a&nbsp;four time&nbsp;New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and&nbsp;optimize&nbsp;every system in the body and mind. Each episode features&nbsp;cutting edge&nbsp;insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living.&nbsp;Thank you to our sponsors!&nbsp;&nbsp;• TRU KAVA | Go to&nbsp;<a href="https://trukava.com/" rel="noopener noreferrer" target="_blank">https://trukava.com/</a>&nbsp;and use code DAVE10 for 10% off.&nbsp;• Generation Lab | Go to&nbsp;<a href="http://generationlab.com/" rel="noopener noreferrer" target="_blank">http://generationlab.com/</a>, use code DAVE20 for $20 off, and see what your body’s really doing behind the surface.&nbsp;•&nbsp;Puori&nbsp;| Use code DAVE at&nbsp;<a href="https://puori.com/DAVE" rel="noopener noreferrer" target="_blank">https://puori.com/DAVE</a>&nbsp;to get 32% off your&nbsp;Puori&nbsp;Fish Oil when you start a subscription.&nbsp;•&nbsp;Screenfit&nbsp;| Get your at-home eye training program for 40% off using code DAVE at&nbsp;<a href="https://www.screenfit.com/dave" rel="noopener noreferrer" target="_blank">https://www.screenfit.com/dave</a>.&nbsp;Dave Asprey&nbsp;is a four-time New York Times bestselling author, founder of&nbsp;Bulletproof Coffee, and the&nbsp;father of biohacking. With over 1,000 interviews and 1 million monthly listeners,&nbsp;The Human Upgrade&nbsp;brings you the knowledge to take control of your biology, extend your longevity, and&nbsp;optimize&nbsp;every system in your body and mind. Each episode delivers&nbsp;cutting-edge&nbsp;insights&nbsp;in&nbsp;health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.&nbsp;New episodes are released every&nbsp;Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.&nbsp;Keywords:&nbsp;stem cell longevity, fasting stem cell rejuvenation, three day fast science, biohacking stem cells, endogenous stem cell mobilization, stem cell decline aging, autophagy fasting longevity, mitochondria stem cells, tissue repair aging, inflammation and aging science, functional medicine longevity podcast, human performance longevity, anti-aging fasting protocol, metabolism and aging, ketosis fasting science, supplements longevity debate, Dave Asprey longevity, Christian Drapeau stem cells, biohacking podcast longevity&nbsp;Resources:&nbsp;&nbsp;&nbsp;• Learn More About&nbsp;Everything STEMREGEN at:&nbsp;<a href="http://stemregen.co/dave30" rel="noopener noreferrer" target="_blank">http://stemregen.co/dave30</a>&nbsp;• Get My 2026 Biohacking Trends Report:&nbsp;<a href="https://daveasprey.com/2026-biohacking-trends-report/" rel="noopener noreferrer" target="_blank">https://daveasprey.com/2026-biohacking-trends-report/</a>&nbsp;• Join My Low-Oxalate 30-Day Challenge:&nbsp;<a href="https://daveasprey.com/2026-low-ox-reset/" rel="noopener noreferrer" target="_blank">https://daveasprey.com/2026-low-ox-reset/</a>&nbsp;• Dave Asprey's Latest News | Go to&nbsp;<a href="https://daveasprey.com/" rel="noopener noreferrer" target="_blank">https://daveasprey.com/</a>&nbsp;to&nbsp;join&nbsp;Inside Track&nbsp;today.&nbsp;&nbsp;• Danger Coffee:&nbsp;<a href="https://dangercoffee.com/discount/dave15" rel="noopener noreferrer" target="_blank">https://dangercoffee.com/discount/dave15</a>&nbsp;&nbsp;&nbsp;• My Daily Supplements:&nbsp;<a href="https://www.shopsuppgradelabs.com/discount/DAVE15" rel="noopener noreferrer" target="_blank">SuppGrade Labs</a>&nbsp;(15% Off)&nbsp;&nbsp;&nbsp;• Favorite Blue Light Blocking Glasses:&nbsp;<a href="https://truedark.com/?coupon-code=DAVEASPREY15&sc-page=shop" rel="noopener noreferrer" target="_blank">TrueDark</a>&nbsp;(15% Off)&nbsp;&nbsp;&nbsp;• Dave Asprey’s BEYOND Conference:&nbsp;<a href="https://beyondconference.com/" rel="noopener noreferrer" target="_blank">https://beyondconference.com</a>&nbsp;&nbsp;&nbsp;• Dave Asprey’s New Book –&nbsp;Heavily Meditated:&nbsp;<a href="https://daveasprey.com/heavily-meditated" rel="noopener noreferrer" target="_blank">https://daveasprey.com/heavily-meditated</a>&nbsp;&nbsp;• Upgrade Collective:&nbsp;<a href="https://www.ourupgradecollective.com/" rel="noopener noreferrer" target="_blank">https://www.ourupgradecollective.com</a>&nbsp;&nbsp;&nbsp;• Upgrade Labs:&nbsp;<a href="https://upgradelabs.com/" rel="noopener noreferrer" target="_blank">https://upgradelabs.com</a>&nbsp;&nbsp;&nbsp;Timestamps:&nbsp;0:00&nbsp;—&nbsp;Trailer&nbsp;1:20&nbsp;— Stem Cell Basics & IV vs Release&nbsp;7:41&nbsp;— Bone Marrow Conversion & Fasting&nbsp;11:01&nbsp;— Stem Cell Decline vs Exhaustion&nbsp;12:39&nbsp;— Releasing Stem Cells&nbsp;14:01&nbsp;— Stem Cells as Signaling Molecules&nbsp;18:13&nbsp;— Stacking Interventions&nbsp;23:31&nbsp;— Dosing & Duration&nbsp;40:42&nbsp;— Daily Repair & Deficits&nbsp;48:20&nbsp;— Resilience & Testing&nbsp;53:17&nbsp;— Inflammation as Signal&nbsp;57:45&nbsp;— Closing&nbsp;See Privacy Policy at <a href="https://art19.com/privacy" rel="noopener noreferrer" target="_blank">https://art19.com/privacy</a> and California Privacy Notice at <a href="https://art19.com/privacy#do-not-sell-my-info" rel="noopener noreferrer" target="_blank">https://art19.com/privacy#do-not-sell-my-info</a>.

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