What if the line between “medicine” and “forbidden” has nothing to do with safety and everything to do with permission? This episode gives you a clear framework for understanding peptides, research chemicals, and performance enhancement so you can think for yourself instead of outsourcing your biology&nbsp;Watch this episode on YouTube for the full video experience:&nbsp;<a href="https://www.youtube.com/@DaveAspreyBPR" rel="noopener noreferrer" target="_blank">https://www.youtube.com/@DaveAspreyBPR</a>&nbsp;Host Dave Asprey sits down with Dylan Gemelli for a candid, unfiltered conversation about the underground world of biohacking, research chemicals, and human performance. Dylan is a long-time biohacker, educator, and researcher who came out of the bodybuilding world and spent more than a decade studying peptides, SARMs, nootropics, and gray-area compounds. He brings first-hand experience, deep research literacy, and a rare ability to explain what these compounds&nbsp;actually do, where the risks are, and why most doctors will never talk about them.&nbsp;Together, they unpack what “research chemicals” really means, why peptides technically fall into that category, and how legality often has little to do with biological reality. They explore compounds like MK-677, S4, and other SARMs, how they interact with growth&nbsp;hormone, muscle, strength, and recovery, and why some of these tools can be more powerful than peptides when used with intention and restraint. Dave also shares his own experiences rebuilding his health using underground tools, why he refuses to ask for permission to take care of his body, and how performance enhancement fits into longevity, metabolism, and real-world function.&nbsp;You’ll&nbsp;Learn:&nbsp;• What research chemicals&nbsp;actually are&nbsp;and why peptides fall into that category&nbsp;• How compounds like MK-677 stimulate growth hormone and affect muscle and recovery&nbsp;• Why SARMs differ from steroids and where the real risks come from&nbsp;• The difference between tobacco and nicotine and why low-dose nicotine can support brain optimization&nbsp;• How performance enhancement fits into longevity, metabolism, and functional medicine thinking&nbsp;• Why strength and neurological drive matter more than size alone&nbsp;• How to think clearly about supplements, nootropics, and biohacking tools without fear or hype&nbsp;• Why taking responsibility for your biology is not cheating&nbsp;Dave Asprey is a&nbsp;four time&nbsp;New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and&nbsp;optimize&nbsp;every system in the body and mind. Each episode features&nbsp;cutting edge&nbsp;insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living.&nbsp;Thank you to our sponsors!&nbsp;&nbsp;•&nbsp;Antarctica Trip | Join me in Antarctica from March 8–17, 2026. Visit&nbsp;<a href="https://www.insiderexpeditions.com/future" rel="noopener noreferrer" target="_blank">https://www.insiderexpeditions.com/future</a>&nbsp;and use code DAVE for $1,000 off.&nbsp;•&nbsp;AirDoctor&nbsp;| Go to&nbsp;<a href="https://airdoctorpro.com/daveasprey" rel="noopener noreferrer" target="_blank">https://airdoctorpro.com/daveasprey</a>&nbsp;and save up to $300 on Air Purifiers.&nbsp;•&nbsp;STEMREGEN | Go to&nbsp;<a href="https://stemregen.co/dave30" rel="noopener noreferrer" target="_blank">https://stemregen.co/dave30</a>&nbsp;and use code DAVE30 for 30% off your next order.&nbsp;•&nbsp;Our Place | Visit&nbsp;<a href="https://fromourplace.com/DAVE" rel="noopener noreferrer" target="_blank">https://fromourplace.com/DAVE</a>&nbsp;and use code DAVE for 10% off sitewide.&nbsp;Dave Asprey&nbsp;is a four-time New York Times bestselling author, founder of&nbsp;Bulletproof Coffee, and the&nbsp;father of biohacking. With over 1,000 interviews and 1 million monthly listeners,&nbsp;The Human Upgrade&nbsp;brings you the knowledge to take control of your biology, extend your longevity, and&nbsp;optimize&nbsp;every system in your body and mind. Each episode delivers&nbsp;cutting-edge&nbsp;insights&nbsp;in&nbsp;health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.&nbsp;New episodes are released every&nbsp;Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.&nbsp;Keywords:&nbsp;biohacking research chemicals, peptide biohacking podcast, underground peptides, SARMs explained, MK-677 growth hormone, performance enhancing drugs science, human performance biohacking, longevity biohacking podcast, neuroplasticity optimization, brain optimization nootropics, mitochondrial optimization biohacking, metabolism and hormones, testosterone optimization science, nicotine brain benefits, modafinil cognitive performance, supplements biohacking debate, functional medicine biohacking, muscle vs strength science, anti-aging performance strategies, Dave Asprey biohacking, Dylan Gemelli biohacking, The Human Upgrade podcast, Smarter Not Harder biohacking&nbsp;Resources:&nbsp;&nbsp;&nbsp;• Learn More About&nbsp;Dylan’s&nbsp;Work&nbsp;And&nbsp;Content At:&nbsp;<a href="https://dylangemelli.com/" rel="noopener noreferrer" target="_blank">https://dylangemelli.com/</a>&nbsp;• Get My 2026 Biohacking Trends Report:&nbsp;<a href="https://daveasprey.com/2026-biohacking-trends-report/" rel="noopener noreferrer" target="_blank">https://daveasprey.com/2026-biohacking-trends-report/</a>&nbsp;• Join My Low-Oxalate 30-Day Challenge:&nbsp;<a href="https://daveasprey.com/2026-low-ox-reset/" rel="noopener noreferrer" target="_blank">https://daveasprey.com/2026-low-ox-reset/</a>&nbsp;• Dave Asprey's Latest News | Go to&nbsp;<a href="https://daveasprey.com/" rel="noopener noreferrer" target="_blank">https://daveasprey.com/</a>&nbsp;to&nbsp;join&nbsp;Inside Track&nbsp;today.&nbsp;&nbsp;• Danger Coffee:&nbsp;<a href="https://dangercoffee.com/discount/dave15" rel="noopener noreferrer" target="_blank">https://dangercoffee.com/discount/dave15</a>&nbsp;&nbsp;&nbsp;• My Daily Supplements:&nbsp;<a href="https://www.shopsuppgradelabs.com/discount/DAVE15" rel="noopener noreferrer" target="_blank">SuppGrade Labs</a>&nbsp;(15% Off)&nbsp;&nbsp;&nbsp;• Favorite Blue Light Blocking Glasses:&nbsp;<a href="https://truedark.com/?coupon-code=DAVEASPREY15&sc-page=shop" rel="noopener noreferrer" target="_blank">TrueDark</a>&nbsp;(15% Off)&nbsp;&nbsp;&nbsp;• Dave Asprey’s BEYOND Conference:&nbsp;<a href="https://beyondconference.com/" rel="noopener noreferrer" target="_blank">https://beyondconference.com</a>&nbsp;&nbsp;&nbsp;• Dave Asprey’s New Book –&nbsp;Heavily Meditated:&nbsp;<a href="https://daveasprey.com/heavily-meditated" rel="noopener noreferrer" target="_blank">https://daveasprey.com/heavily-meditated</a>&nbsp;&nbsp;• Upgrade Collective:&nbsp;<a href="https://www.ourupgradecollective.com/" rel="noopener noreferrer" target="_blank">https://www.ourupgradecollective.com</a>&nbsp;&nbsp;&nbsp;• Upgrade Labs:&nbsp;<a href="https://upgradelabs.com/" rel="noopener noreferrer" target="_blank">https://upgradelabs.com</a>&nbsp;&nbsp;&nbsp;Timestamps:&nbsp;0:00&nbsp;- Introduction&nbsp;1:28&nbsp;- SARMs & Research Chemicals&nbsp;7:43&nbsp;- 29 Pounds of Muscle in 6 Weeks&nbsp;10:20&nbsp;- MK-677 & Growth Hormone&nbsp;16:41&nbsp;- Vegan Diet Disaster&nbsp;18:30&nbsp;- From Bodybuilding to Biohacking&nbsp;21:31&nbsp;- Diet Transformation & Metabolism&nbsp;29:14&nbsp;- Reversing Heart Plaque&nbsp;33:50&nbsp;- Exercise, Cardio & Longevity&nbsp;44:16&nbsp;- Testosterone, TRT &&nbsp;Kyzatrex&nbsp;50:06&nbsp;- Healthcare Freedom&nbsp;53:23&nbsp;- Medical Freedom&nbsp;See Privacy Policy at <a href="https://art19.com/privacy" rel="noopener noreferrer" target="_blank">https://art19.com/privacy</a> and California Privacy Notice at <a href="https://art19.com/privacy#do-not-sell-my-info" rel="noopener noreferrer" target="_blank">https://art19.com/privacy#do-not-sell-my-info</a>.

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