The Human Upgrade: Biohacking for Longevity & Performance podcast

The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

 

#1485

AI Expert Says: Humans Are Just Mystical Meat Robots : 1429

What if understanding how AI thinks could reveal uncomfortable truths about how your own b... more

19 hrs Ago

57 MINS

57:57

19 hrs Ago


#1484

How I Finally FIXED My Terrible Sleep After 18 Years : 1428

Block toxic light with these glasses: https://truedark.com/discount/DAVETUBE Think 8 hours... more

08 Mar 2026

09 MINS

09:42

08 Mar 2026


#1483

WW3 Doomscrolling, 5 Minute Sleep Hack, Diet Wars, Dopamine Supplements : 1427

This week’s stories: Healthy Diets That Offset "Bad Genes" A major UK Biobank study of ove... more

06 Mar 2026

11 MINS

11:31

06 Mar 2026


#1482

Your Brain Is 0.5% Plastic (Here’s How to Flush It) : 1426

Microplastics are invading your brain, blood, hormones, and fat tissue, and most people ha... more

05 Mar 2026

56 MINS

56:09

05 Mar 2026


#1481

Why Are Hackers Microdosing “Sex Drugs” Now? : 1425

Most doctors treat the average patient. But you are not average, and this episode gives yo... more

03 Mar 2026

53 MINS

53:16

03 Mar 2026


#1480

A-List Celebrities' Anti-Aging Hack to Look 30 At 50 (Drug-free) : 1424

What if the secret to living longer wasn't locked in a lab, but hiding in plain sight? And... more

01 Mar 2026

14 MINS

14:50

01 Mar 2026


#1479

Mexican Cartel Biohacking, Google Anti-Aging Breakthrough, Measles Is Back, Age Reversal In 2026 : 1...

This week’s stories: Sinclair’s This Is the Test: Are we about to see agereversalin humans... more

27 Feb 2026

09 MINS

09:22

27 Feb 2026


#1478

The Secret to Staying DANGEROUS After 50 : 1422

Peptides can change how you heal, lean out, build muscle, and age, but only if you stop ta... more

26 Feb 2026

1 HR 00 MINS

1:00:34

26 Feb 2026


#1477

The Home Laser That Reverses Skin Age By 20 Years : 1421

Your skin is not just a cosmetic surface.It’sa living organ that responds to signals, and ... more

24 Feb 2026

57 MINS

57:02

24 Feb 2026


#1476

I Tested The Most Dangerous Viral Brain Hack : 1420

Most people try to fix brain fog and focus issues with caffeine or nootropics, but those a... more

22 Feb 2026

11 MINS

11:57

22 Feb 2026


#1475

Plastic in Your Testicles, AI Sleep Scans, The 29% Weight Loss Drug : 1419

This episode covers: • Microplastics AreDestroyingMaleFertility and Metabolism New researc... more

20 Feb 2026

11 MINS

11:06

20 Feb 2026


#1474

Change Your Morning, Change Your Life – Hal Elrod : 1418

Meet a man who makes miracles happen. Today,werevistmy conversation withHal Elrod, author ... more

19 Feb 2026

1 HR 12 MINS

1:12:44

19 Feb 2026


#1473

The Secret to Looking Younger is in Mushrooms (And Chocolate?) : 1417

Your gray hair, thinning lashes, brain fog, and that low energy feeling after 30 might all... more

17 Feb 2026

1 HR 06 MINS

1:06:53

17 Feb 2026


#1472

Low Testosterone Starts In Your Eyes (Avoid This Before Bed) : 1416

https://truedark.com/discount/DAVETUBE Most people believe testosterone declines simply be... more

15 Feb 2026

14 MINS

14:14

15 Feb 2026


#1471

Jet Lag Superdrug, 25% Dementia Drop, Coffee Brain Aging, Kratom Shakeup : 1415

This episode covers: • Mic-628 Could Reset Your Body Clock and Cut Jet Lag in Half A new c... more

13 Feb 2026

09 MINS

09:39

13 Feb 2026


#1470

Turn Off Your WiFi Tonight and See What Happens to Your Sleep : 1414

Your phone, your lighting, and yourWiFican mess with your sleep and energy more than your ... more

12 Feb 2026

47 MINS

47:09

12 Feb 2026


#1469

The Secret Peptides and Underground Compounds Doctors Won’t Talk About : 1413

What if the line between “medicine” and “forbidden” has nothing to do with safety and ever... more

10 Feb 2026

59 MINS

59:26

10 Feb 2026


#1468

Why Your Muscles Break Down After 40 (Do This To Reverse It) : 1412

Your muscles play a far bigger role in aging than most people realize. As you get older, t... more

08 Feb 2026

10 MINS

10:16

08 Feb 2026


#1467

Biohackers in the Epstein Files, Generic GLP-1s, Continuous Ketone Monitors, and more... : 1411

This episode covers: • Longevity InfluenceInTheEpstein Files A new DOJ document release ti... more

06 Feb 2026

07 MINS

07:11

06 Feb 2026


#1466

Why 18-Year-Olds Wake Up Fresh (And You Don't) : 1410

18-year-olds wake up fresh because their repair system still works. This episode shows you... more

05 Feb 2026

58 MINS

58:50

05 Feb 2026


#1465

STOP Intermittent Fasting If You Want to Stay Young : 1409

STOP intermittent fasting if you think it automatically keeps you young. In this episode,y... more

03 Feb 2026

1 HR 17 MINS

1:17:18

03 Feb 2026


#1464

Aging Starts In Your Legs (Here’s The Fix) : 1408

Most people think aging starts with wrinkles, gray hair, or memory loss. It doesn’t. Aging... more

01 Feb 2026

08 MINS

08:19

01 Feb 2026


#1463

The Nobel Prize Molecule That Nearly Doubles Lifespan : 1407

In the late 1990s, a strange carbon molecule quietly delivered the single longest lifespan... more

30 Jan 2026

1 HR 04 MINS

1:04:27

30 Jan 2026


#1462

Meet the Governor Who Wants Humans to Become Cyborgs : 1406

Aging is not something Zoltan Istvan plans to accept quietly. He wants to treat death like... more

29 Jan 2026

1 HR 07 MINS

1:07:11

29 Jan 2026


#1461

Your Butt is a Longevity Organ (Here’s how to train it!) | Gabrielle Lyon : 1405

Your butt is not about aesthetics. It is a longevity organ that directlyimpactsmetabolism,... more

27 Jan 2026

1 HR 02 MINS

1:02:20

27 Jan 2026