Could a single molecule be the difference between vibrant longevity and early decline?&nbsp;Dr. Andy Salzman—Harvard-trained physician, scientist, and creator of the first PARP1 inhibitor—joins Dave to reveal the&nbsp;real&nbsp;key to living longer, fighting disease, and maximizing your energy:&nbsp;NAD.&nbsp;This master molecule fuels your&nbsp;mitochondria, DNA repair, and cellular resilience, but here’s the catch—it plummets as you age.&nbsp;That means more fatigue, brain fog, inflammation, and higher risks of disease. But what if you could&nbsp;stop the decline and even reverse it?&nbsp;Dr. Salzman breaks down the game-changing science behind&nbsp;NAD, CD38, and cellular repair—and the&nbsp;fastest, most effective ways to optimize your levels for peak performance, health, and longevity.&nbsp;Get ready to rethink everything you thought you knew about aging, pharmaceuticals vs. supplements, and the&nbsp;radical new approach&nbsp;to living better, longer.&nbsp;What You’ll Learn:&nbsp;•&nbsp;The #1 reason your NAD is disappearing—and how to fix it&nbsp;•&nbsp;Why NAD is the missing link in energy, DNA repair, and disease prevention&nbsp;•&nbsp;The hidden enzyme (CD38) that’s sabotaging your longevity&nbsp;•&nbsp;How to supercharge mitochondria, optimize blood flow, and fight aging at the source&nbsp;•&nbsp;Why the supplement industry has it wrong—and the best way to boost NAD naturally&nbsp;•&nbsp;The shocking truth about the FDA, pharmaceuticals, and the future of anti-aging medicine&nbsp;Resources:&nbsp;&nbsp;• Dave Asprey’s New Book - Heavily Meditated: <a href="https://daveasprey.com/heavily-meditated/" rel="noopener noreferrer" target="_blank">https://daveasprey.com/heavily-meditated/</a>&nbsp;• Andrew Salzman’s Instagram –&nbsp; <a href="https://www.instagram.com/andrew_salzman/?hl=en" rel="noopener noreferrer" target="_blank">https://www.instagram.com/andrew_salzman/?hl=en</a>&nbsp;•	2025 Biohacking Conference: <a href="https://biohackingconference.com/2025" rel="noopener noreferrer" target="_blank">https://biohackingconference.com/2025</a>&nbsp;•	Danger Coffee: <a href="https://dangercoffee.com/" rel="noopener noreferrer" target="_blank">https://dangercoffee.com</a>&nbsp;•	Dave Asprey’s Website: <a href="https://daveasprey.com/" rel="noopener noreferrer" target="_blank">https://daveasprey.com</a>&nbsp;•	Dave Asprey’s Linktree: <a href="https://linktr.ee/daveasprey" rel="noopener noreferrer" target="_blank">https://linktr.ee/daveasprey</a>&nbsp;•	Upgrade Collective – Join The Human Upgrade Podcast Live: <a href="https://www.ourupgradecollective.com/" rel="noopener noreferrer" target="_blank">https://www.ourupgradecollective.com</a>&nbsp;•	Own an Upgrade Labs: <a href="https://ownanupgradelabs.com/" rel="noopener noreferrer" target="_blank">https://ownanupgradelabs.com</a>&nbsp;•	Upgrade Labs: <a href="https://upgradelabs.com/" rel="noopener noreferrer" target="_blank">https://upgradelabs.com</a>&nbsp;•	40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: <a href="https://40yearsofzen.com/" rel="noopener noreferrer" target="_blank">https://40yearsofzen.com</a>&nbsp;Timestamps:&nbsp;00:00&nbsp;Trailer&nbsp;01:07&nbsp;Introduction and Episode Overview&nbsp;02:29&nbsp;Meet Dr. Andy Salzman&nbsp;02:36&nbsp;From Physician to Researcher&nbsp;03:39&nbsp;Pharmaceuticals vs. Nutritionals&nbsp;04:17&nbsp;The Role of NAD in Longevity&nbsp;06:32&nbsp;Challenges in Longevity Research&nbsp;12:58&nbsp;Understanding NAD and PARP&nbsp;14:34&nbsp;NAD’s Impact on Health&nbsp;23:19&nbsp;Gut Health and Longevity&nbsp;27:43&nbsp;Innovations in NAD Supplementation&nbsp;41:27&nbsp;Customer Feedback and Product Effectiveness&nbsp;42:41&nbsp;Surprising Benefits of NAD for Sexual Health&nbsp;44:47&nbsp;NAD and Vascular Health&nbsp;48:46&nbsp;NAD’s Role in Aging and Longevity&nbsp;54:03&nbsp;NAD and Lifestyle Choices&nbsp;01:03:02&nbsp;NAD and Cognitive Function&nbsp;01:06:18&nbsp;NAD and Exercise&nbsp;01:13:42&nbsp;NAD and Sleep&nbsp;01:21:54&nbsp;Final Thoughts on NAD and Longevity&nbsp;See Privacy Policy at <a href="https://art19.com/privacy" rel="noopener noreferrer" target="_blank">https://art19.com/privacy</a> and California Privacy Notice at <a href="https://art19.com/privacy#do-not-sell-my-info" rel="noopener noreferrer" target="_blank">https://art19.com/privacy#do-not-sell-my-info</a>.

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