The Human Upgrade: Biohacking for Longevity & Performance podcast

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The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

 

#1602

Vagus Nerve Memory, Cat Cancer Genes, Inherited Intelligence, Mulberry Microbes, and Vitamin D : 15...

Vagus Nerve Stimulation Improves Cognitive Scores in a Small Trial In a 24-week trial invo... more

Yesterday

10 MINS

10:37

Yesterday


#1601

Dave’s Anti-Aging Skincare Routine: Exosomes, Methylene Blue & NAD+ : 1547

Visit [https://www.younggoose.com/] (https://www.younggoose.com/) and use codeASPREY10to s... more

01 Oct 2026

47 MINS

47:03

01 Oct 2026


#1600

The Silent Fatty Liver Epidemic: Why Thin, Sober People Are Still at Risk : 1546

Visit [LoveYourLiver.com] (https://loveyourliver.com/discount/Dave2026?redirect=%2Fproduct... more

29 Sep 2026

56 MINS

56:58

29 Sep 2026


#1599

Every Way to Melt Visceral Fat FAST In 14 Minutes : 1545

Try TrueDark glasses: https://truedark.com Try Danger Coffee: https://dangercoffee.com/dis... more

27 Sep 2026

14 MINS

14:24

27 Sep 2026


#1598

Ozempic Hair, GLP-1 Kids, Gut-Brain Anxiety, Food Additives, Taurine, and more : 1544

Novo Nordisk Eyes Hair-Loss Market in Consumer-Health Expansion Novo Nordisk, the company ... more

25 Sep 2026

14 MINS

14:40

25 Sep 2026


#1597

The Best Singular Hack To Change EVERYTHING About Your Life : 1543

Back again with one of the best episodes we've done on the channel. So good that we had to... more

24 Sep 2026

1 HR 13 MINS

1:13:45

24 Sep 2026


#1596

15g Every Morning for Anti-Aging Mitochondria : 1541

Catharine Arnston on Spirulina, Chlorella, Mitochondria, Detox, Brain Energy, and Longevit... more

22 Sep 2026

58 MINS

58:42

22 Sep 2026


#1595

I Wasted 10 Years Stuck With Brain Fog Until I Learned This : 1540

Try TrueDark glasses: https://truedark.com Try Danger Coffee: https://dangercoffee.com/dis... more

20 Sep 2026

20 MINS

20:31

20 Sep 2026


#1594

Teal Swan - Beyond the Veil of Ego, AI & Wisdom : 1539

Back with another all-time classic. Teal's is one of those episodes I keep going back to b... more

18 Sep 2026

1 HR 02 MINS

1:02:36

18 Sep 2026


#1593

How to Hack Your Smell for Memory and Longevity WHILE YOU SLEEEP! : 1538

Dr. Michael Leon on Smell Training, Memory, Sleep, Alzheimer’s Risk, and Brain Longevity Y... more

17 Sep 2026

54 MINS

54:16

17 Sep 2026


#1592

Josh Duhamel on Nootropics, Peptides, and Testosterone at 53 : 1537

**Visit [https://www.gatlan.com/] (https://www.gatlan.com/) and use cod ‘DAVE’ to unlock a... more

16 Sep 2026

55 MINS

55:33

16 Sep 2026


#1591

The Peptide Secrets to a Youthful Face : 1536

Carolina Reis de Oliveira on Reversing Skin Age, Menopause, GLP-1 Skin, and the Science of... more

15 Sep 2026

55 MINS

55:39

15 Sep 2026


#1590

What 36 Hours Without Sugar Does to Your Body : 1535

Try TrueDark glasses: https://truedark.com Try Danger Coffee: https://dangercoffee.com/dis... more

13 Sep 2026

12 MINS

12:05

13 Sep 2026


#1589

New Seafood Superfood, Apple Watch Health Age, Botanical Drugs, Cannabis IQ, and Blueberries : 1534

Sea Squirt Plasmalogens Show Brain And Aging Benefits In Old Mice Aged mice given purified... more

11 Sep 2026

09 MINS

09:48

11 Sep 2026


#1588

Everything You Need To Know About Your Poop | Gut Surgeon Explains : 1533

Dr. Karan Rajan on Fiber Fermentation, Sodium Myths, and What Your Poop Reveals About Dise... more

08 Sep 2026

1 HR 09 MINS

1:09:00

08 Sep 2026


#1587

If I Had To Lose 50 Pounds FAST, I’d Do THIS : 1532

Try TrueDark glasses: https://truedark.com Try Danger Coffee: https://dangercoffee.com/dis... more

06 Sep 2026

10 MINS

10:03

06 Sep 2026


#1586

Raw Garlic, Egg Yolks, Heat Strokes, and Melatonin : 1531

Raw Garlic "Ultimate Biohack" Trend Faces Scientific Scrutiny Raw garlic has gone viral as... more

04 Sep 2026

07 MINS

07:48

04 Sep 2026


#1585

Jenny McCarthy | The 3 Questions You’re NEVER Supposed to Ask : 1530

Jenny McCarthy on Reversing Autism, Healing Mold Toxicity, and the Biohacking Protocol Big... more

03 Sep 2026

1 HR 58 MINS

1:58:16

03 Sep 2026


#1584

3 Longevity Drugs I QUIT (And the 4 I Take Instead) : 1529

The 3 "Longevity Drugs" That Fail the Data, and 4 Repurposed Ones Worth Considering Back w... more

01 Sep 2026

35 MINS

35:54

01 Sep 2026


#1583

7 Brain Compounds I Take For Superhuman Focus : 1528

Try TrueDark glasses: https://truedark.com Try Danger Coffee: https://dangercoffee.com/dis... more

30 Aug 2026

09 MINS

09:43

30 Aug 2026


#1582

Change Your Morning, Change Your Life! Hal Elrod : 1527

Starting your weekend off right, with the king of mindset. We had to replay this one becau... more

28 Aug 2026

1 HR 13 MINS

1:13:33

28 Aug 2026


#1581

Learn THIS And You’ll Become Impossible To Trigger : 1526

Jonny Miller on Nervous System Mastery, Grief, and Why High Performers Can't Afford to Sta... more

27 Aug 2026

1 HR 01 MINS

1:01:46

27 Aug 2026