The Human Upgrade: Biohacking for Longevity & Performance podcast

The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

 

#1451

Reversing The American Food Pyramid | Calley Means : 1395

Back in 2024 with Calley Meansat South by Southwest,wesat down andtalked about his mission... more

20 hrs Ago

1 HR 10 MINS

1:10:48

20 hrs Ago


#1450

The Willpower Drug: How to Supplement Discipline : 1394

Creatine is a hot subject right now, butI’mguessing you might not know as much about it as... more

Yesterday

1 HR 20 MINS

1:20:53

Yesterday


#1449

How Long Can Humans Really Live… (with Dan Buettner) : 1393

You’reabout to hear one of the most honest longevity conversations ever recorded. Thisco h... more

06 Jan 2026

54 MINS

54:24

06 Jan 2026


#1448

This Legal Boner Pill Is Hiding A Future Heart Attack : 1392

Most men think ED is just a performance issue. It’s not. It’s one of the earliest warning ... more

04 Jan 2026

19 MINS

19:06

04 Jan 2026


#1447

Biohacking News Weekly Update : 1391

This episode covers: •Colon Cancer in the Young and Why Risk May Start in Infancy New repo... more

02 Jan 2026

07 MINS

07:54

02 Jan 2026


#1446

The Secret Federal Plan to Feed Us Legal Poison : 1390

You’reabout to learn how government approved food policies, regulatory loopholes, and corp... more

01 Jan 2026

52 MINS

52:45

01 Jan 2026


#1445

These 7 Superfoods Are Secretly Wrecking Your Body : 1389

This solo masterclass on oxalates explains why many people who eat clean still struggle wi... more

30 Dec 2025

32 MINS

32:51

30 Dec 2025


#1444

I Lost 100 Pounds By Fasting Like THIS (The Missing Step) : 1387

This video reveals the hidden mistake most people make when fasting that causes muscle los... more

28 Dec 2025

12 MINS

12:42

28 Dec 2025


#1443

Biohacking News Weekly Update : 1388

This episode covers: • Trump Drug Pricing Deals and Access to Longevity Medications New dr... more

26 Dec 2025

12 MINS

12:28

26 Dec 2025


#1442

How to Get and Stay Sober in 2026 (The Biohacker’s Guide) | Luke Storey : 1386

The holidays are when drinking quietly ramps up for a lot of people. More parties, more st... more

25 Dec 2025

1 HR 12 MINS

1:12:51

25 Dec 2025


#1441

What it takes to be “Young Forever!” | Mark Hyman : 1385

Most conversations about longevity focus on tactics. This episode breaks down the biology ... more

23 Dec 2025

1 HR 02 MINS

1:02:30

23 Dec 2025