The Human Upgrade: Biohacking for Longevity & Performance podcast

The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

 

#1497

Your Organic Protein Powder Is Slowly Killing You : 1441

Most people buying "clean" supplements are unknowingly loading their bodies with heavy met... more

15 hrs Ago

1 HR 02 MINS

1:02:24

15 hrs Ago


#1496

This Legal Sleep Powder Beats Melatonin Every Time : 1440

Try TrueDark (with my discount): https://truedark.com/discount/DAVETUBE I have spent 20 ye... more

29 Mar 2026

15 MINS

15:26

29 Mar 2026


#1495

I Injected Stem Cells Into My Penis (Here's What Happened) : 1439

Your brain is hardware, and if the hardware is broken, no supplement stack, nootropic, or ... more

27 Mar 2026

31 MINS

31:10

27 Mar 2026


#1494

Arthur Brooks | Why Your Life Has No Meaning : 1438

What if the real reason you feel stuck, anxious, or unfulfilled has nothing to do with you... more

26 Mar 2026

57 MINS

57:31

26 Mar 2026


#1493

This Popular Fat Loss Shortcut Destroys Your Youth : 1437

Your gut microbiome controls your brain chemistry, your stress response, your sleep, your ... more

24 Mar 2026

55 MINS

55:36

24 Mar 2026


#1492

Give Me 21 Minutes And I'll Give You Perfect Vision Naturally : 1436

Try TrueDark (with my discount): https://truedark.com/discount/DAVETUBE I transformed my v... more

22 Mar 2026

21 MINS

21:08

22 Mar 2026


#1491

SNL Roasts MAHA, Pistachios Slap, ChatGPT Doctor Stats, Colon Cancer Under 50, and more... : 1435

This week's stories: *SNL Roasts the MAHA Movement Saturday Night Live took direct aim at ... more

20 Mar 2026

12 MINS

12:36

20 Mar 2026


#1490

Here's Why You Still Feel Like Sh*t After Doing Everything Right... : 1434

Your thyroid controls your energy, your metabolism, your testosterone, your mood, and your... more

19 Mar 2026

1 HR 01 MINS

1:01:20

19 Mar 2026


#1489

The Awakening Within Cells: Healing Breakthroughs No One Can Ignore : 1433

What if a glowing pyramid sitting in your living room could restructure your biology, comp... more

17 Mar 2026

58 MINS

58:56

17 Mar 2026


#1488

This Nobel Prize Discovery Reverses Aging In 72 Hours : 1432

Is aging an inevitable decline, or just a "repair backlog" your body hasn't cleared yet?. ... more

15 Mar 2026

16 MINS

16:47

15 Mar 2026


#1487

Your Telomeres Are a Lie, Bats Beat Aging, Sleep Meds Ruin Mornings, CO's Silent Kill, and more... :...

This week’s stories: Smartphone App Catches What Sleep Trackers Miss A 2026 trial found th... more

13 Mar 2026

12 MINS

12:34

13 Mar 2026


#1486

Your Penis Is a Longevity Organ (Here's How to Hack It) : 1430

Testosterone levels in 40-year-old men are 30 percent lower than their fathers, and most d... more

12 Mar 2026

1 HR 03 MINS

1:03:19

12 Mar 2026


#1485

AI Expert Says: Humans Are Just Mystical Meat Robots : 1429

What if understanding how AI thinks could reveal uncomfortable truths about how your own b... more

10 Mar 2026

57 MINS

57:57

10 Mar 2026


#1484

How I Finally FIXED My Terrible Sleep After 18 Years : 1428

Block toxic light with these glasses: https://truedark.com/discount/DAVETUBE Think 8 hours... more

08 Mar 2026

09 MINS

09:42

08 Mar 2026


#1483

WW3 Doomscrolling, 5 Minute Sleep Hack, Diet Wars, Dopamine Supplements : 1427

This week’s stories: Healthy Diets That Offset "Bad Genes" A major UK Biobank study of ove... more

06 Mar 2026

11 MINS

11:31

06 Mar 2026


#1482

Your Brain Is 0.5% Plastic (Here’s How to Flush It) : 1426

Microplastics are invading your brain, blood, hormones, and fat tissue, and most people ha... more

05 Mar 2026

56 MINS

56:09

05 Mar 2026


#1481

Why Are Hackers Microdosing “Sex Drugs” Now? : 1425

Most doctors treat the average patient. But you are not average, and this episode gives yo... more

03 Mar 2026

53 MINS

53:16

03 Mar 2026