Gary takes on the real issues that the mainstream media is afraid to tackle. Tune in to find out the latest about health news, healing, politics, and the economy.


The Gary Null Show

HEALTH NEWS
The mechanism of black ginseng extract in alleviating inflammatory aging
Eating the Wrong Carbs May Raise Your Dementia Risk
Mix of different types of physical activity may be best for longer life
Oral bacterium may promote breast cancer development and spread
Severe vitamin D deficiency linked to higher hospitalizations for respiratory tract infections

The Gary Null Show - 1-23-26

How to Repurpose and Restart Your Life When Your Current Path No Longer Works
Gary Null PhD
At some point, every person who wants a meaningful life must do something most people
avoid: stop. Stop long enough to turn off the distractions and ask, with real seriousness,
what the purpose and meaning of this life is. Then comes the harder follow-up: am I
honoring that purpose—or am I merely performing a routine that looks like living? And if I’m
honest, which pieces of my life no longer make sense to me?

The Gary Null Show 1-22-26

The Second Part of How to Overcome Our Addictive Behavior: The Thirteenth Step

The Gary Null Show 1-21-26

HEALTH NEWS
 


<ul>
<li>
Vitamin C plus Grape Seed Extract Outperforms Chemotherapy for Tumor Reduction
</li>
<li>
Salted foods may increase cancer risk: Japanese study
</li>
<li>
Why a life-threatening sedative is being prescribed more often for seniors
</li>
<li>
Blueberry Drink Protects Mice from Diabetes, Obesity
</li>
<li>
Microplastics Can Rewire Sperm, Triggering Diabetes in the Next Generation
</li>
</ul>

The Gary Null Show - 1-20-26

How to Overcome Our Addictive Behavior: The 13 th Step.
“All crises show us what we’ve avoided.”
—Gary Null, PhD
Today we’re dealing with tens of millions of Americans who suffer from some form of
addictive behavior.

The Gary Null Show - 1-19-26

HEALTH NEWS
 



<ul>
<li>
Probiotics emerge as a potent tool against depression and anxiety
</li>
<li>
Altered microbiome: Oral bacteria play a role in chronic liver disease, study reveals
</li>
<li>
Health issues linked to cosmetic jab complications
</li>
<li>
From yoga to awe walks: Many paths lead to better mental health, largest analysis of well-being interventions finds
</li>
<li>
Weight loss drugs may cause nutritional deficiencies without proper guidanc
</li>
</ul>



 
 

 

Probiotics emerge as a potent tool against depression and anxiety
University of Calgary (Canada), January 14 2026 (Natural News)

For decades, the standard pharmaceutical approach to treating depression and anxiety has dominated treatment options, despite significant drawbacks including delayed effects, debilitating side effects and high relapse rates. Now, compelling new research is challenging this paradigm by pointing to a surprising source of relief: the gut. A comprehensive scientific analysis, synthesizing data from over 1,400 clinically diagnosed patients, reveals that probiotics—beneficial bacteria readily available as supplements—can produce substantial reductions in both depressive and anxious symptoms.
 
The analysis major findings include:

 
 
<ul>
<li><ul>
<li>A major analysis of 23 clinical trials finds probiotics can significantly reduce symptoms of depression and anxiety in clinically diagnosed patients.</li>
</ul>
</li>
</ul>
 
<ul>
<li><ul>
<li>The benefits, appearing within 4-8 weeks, were comparable to some conventional antidepressants but without the same side-effect profile.</li>
</ul>
</li>
</ul>
 
<ul>
<li><ul>
<li>The gut-brain axis, a communication network largely ignored by conventional psychiatry, is central to understanding this connection.</li>
</ul>
</li>
</ul>
 
<ul>
<li><ul>
<li>Single-strain probiotic supplements, particularly certain Lactobacillus and Bifidobacterium species, showed the strongest mental health effects.</li>
</ul>
</li>
</ul>
 
<ul>
<li><ul>
<li>This research supports a holistic view of mental wellness, where gut health is a foundational component of treatment.</li>
</ul>
</li>
</ul>
 
 

Altered microbiome: Oral bacteria play a role in chronic liver disease, study reveals
Technical University Munich (Germany), January 15 2026 (Medical Xpress)
Each year, more than two million people die from advanced chronic liver disease (ACLD). Previous research has linked gut microbiome disruptions to this condition and suggested that bacteria typically found in the mouth may colonize the gut.



A new study published in Nature Microbiology now shows that identical bacterial strains occur in both the mouth and gut of patients with advanced chronic liver disease and also reveals a mechanism by which oral bacteria affect gut health. The researchers also found that this process coincides with worsening liver health.
Researchers analyzed bacterial populations in saliva and stool samples from patients. The team found that both the gut and oral microbiome undergo significant changes as liver disease worsened, where changes to the oral microbiome were already detectable at earlier disease stages.
In healthy individuals, bacterial communities differ substantially between body sites. In patients with liver disease, however, oral and gut microbiomes became increasingly similar as the disease progressed and nearly identical bacterial strains were recovered from the mouth and gut of patients.
"These strains are typically found in the mouth and are rarely present in the healthy gut. However, we observed increases in the absolute abundances of these oral bacteria in patients with advanced chronic liver disease. This strongly suggests that these bacteria translocate from the mouth and colonize the gut," explains Melanie Schirmer, Professor of Translational Microbiome Data Integration at TUM.





 


Health issues linked to cosmetic jab complications
Anglia Ruskin University (UK), January 9 2026 (Eurekalert)


 



Patients with chronic illnesses face a significantly higher risk of complications from cosmetic botulinum toxin injections, commonly known as Botox, according to a major UK study.
Researchers from Anglia Ruskin University (ARU) surveyed 919 adults who had received botulinum toxin treatments for aesthetic reasons. The study, published in Aesthetic Surgery Journal, is the largest of its kind to have been carried out in the UK. Botulinum toxin injections are among the UK’s most popular cosmetic procedures, with an estimated 900,000 treatments performed every year.
Researchers found that underlying conditions such as type 1 diabetes, thyroid disorders, chronic migraine and skin disease dramatically increase the likelihood of adverse effects.
According to the study, people with type 1 diabetes were 92 times more likely to experience nausea after treatment compared to those without the condition. Those with thyroid disorders and chronic migraine sufferers had an approximately 10-fold increase in the risk of nausea.
Other complications associated with pre-existing conditions included headaches, bruising, muscle weakness and persistent eyelid droop (ptosis). Patients with cataracts were 30 times more likely to report headaches, and those with prior injuries had a 21-fold increased risk of losing facial expression.
 
From yoga to awe walks: Many paths lead to better mental health, largest analysis of well-being interventions finds
Swansea University (UK), January 15 2026 (Medical Xpress)
New research by Swansea experts has provided the largest ever comparison of well-being-focused interventions delivered to adults.
The team reviewed 183 randomized controlled trials, representing almost 23,000 participants, and evaluated 12 categories of interventions ranging from psychological, physical, mind–body, and nature-based approaches to find out more. Their research was the first interdisciplinary comparison carried out across psychological, physical, mind-body and environmental interventions.
The study gives an integrated view of how different disciplines contribute to well-being. By focusing on general adult samples rather than clinical groups, it provides evidence that will be relevant to developing public health, education, workplace well-being, and community programs.
The researchers' key findings were:
<ul>
<li>Most interventions improved well-being compared with inactive control groups;</li>
<li>Strongest effects were found for combined exercise plus psychological interventions (for example, awe walks or meditation combined with walking);</li>
<li>Mind–body interventions showed consistently moderate, reliable effects;</li>
<li>Exercise alone produced similar benefits to many psychological interventions; and,</li>
<li>Positive psychology interventions—both single-component and multicomponent—were also effective.</li>
</ul>
The analysis shows that there is no single route to improving well-being. Mindfulness, compassion-based approaches, yoga, exercise and positive psychology interventions all showed moderate benefits compared with control groups, and combining physical activity with psychological interventions appeared particularly promising.
 








Weight loss drugs may cause nutritional deficiencies without proper guidance



 
 




University College London & Cambridge, January 7 2026 (News-Medical)

People prescribed the new generation of weight loss drugs may not receive sufficient nutritional guidance to support safe and sustainable weight loss, leaving them vulnerable to nutritional deficiencies and muscle loss, say experts at UCL and the University of Cambridge.
In research published today in Obesity Reviews, the team found a lack of robust evidence surrounding nutritional advice and support and the impact this has on factors such as calorie intake, body composition, protein adequacy, and patient experiences.
Weight loss drugs such as semaglutide and tirzepatide – available under brand names including Ozempic, Wegovy and Mounjaro – mimic the naturally-occurring hormone glucagon like peptide-1 (GLP-1), released into the blood in response to eating. The drugs suppress appetite, increase a feeling of being full, and reduce food cravings.
These drugs can reduce calorie intake by between 16-39 %, making them a powerful tool to help people living with obesity and being overweight. However, there has been little research to examine their impact on diet quality, protein intake, or adequacy of micronutrients (vitamins and minerals).


The researchers identified just 12 studies that looked at nutrition and diet alongside treatment with semaglutide or tirzepatide. Given the widespread – and increasing – use of these medications and the urgency of providing advice to individuals using the drugs, there was insufficient evidence from the studies to recommend strict low-fat diets to complement the weight loss drugs. Some observational studies found that people on the treatments often consumed excessive levels of total and saturated fat.

These medications are transforming obesity care, but we know very little about how they shape people's daily lives, including changes in appetite, eating patterns, wellbeing, and quality of life.

The Gary Null Show 1-16-26

HEALTH NEWS
 


<ul>
<li>
Can exercise turn back the clock on your brain? New study says yes
</li>
<li>
Why leaving things unfinished messes with your mind
</li>
<li>
Short-term, calorie-restrictive diet improves Crohn’s disease symptoms
</li>
<li>
Higher daylight exposure improves cognitive performance, study finds
</li>
<li>
Breastfeeding may lower mums’ later life depression/anxiety risks for up to 10 years after pregnancy
</li>
</ul>


 
 

Can exercise turn back the clock on your brain? New study says yes
AdventHealth Research Institute, January 13 2026 (Eurekalert)

A simple, steady exercise routine may help your brain stay biologically younger, supporting clearer thinking, stronger memory, and a greater sense of whole-person well-being.  
The study found that adults who followed a year-long aerobic exercise program had brains that appeared nearly a year “younger” than those who didn’t change their activity levels.  
Published in the Journal of Sport and Health Science, the study explored whether regular aerobic exercise could slow, or even reverse “brain age,” a magnetic resonance imaging (MRI)-based biomarker of how old your brain looks compared to your actual age. A higher brain-predicted age difference (brain-PAD), indicates an older-appearing brain and has been linked to poorer physical and cognitive function and increased risk of mortality in previous research. 
In this clinical trial, 130 healthy adults aged 26–58 were randomly assigned to either a moderate-to-vigorous aerobic exercise group or a usual-care control group. The exercise group completed two supervised 60-minute sessions per week in a laboratory plus home-based exercise to reach about 150 minutes of aerobic activity per week, aligning with the American College of Sports Medicine’s physical activity guidelines. Brain MRI and cardiorespiratory fitness, measured as peak oxygen uptake (VO2peak), were assessed at the beginning and end of the 12-month period. 
Over 12 months, participants in the exercise group showed a measurable reduction in brain age, while the control group showed a slight increase. On average, the exercise group’s brain-PAD decreased by about 0.6 years, indicating a younger-appearing brain at follow-up. In contrast, the control group’s brains appeared about 0.35 years older, a change that was not statistically significant. Overall, the between-group difference in brain age was nearly one year, favoring the exercise group.



 
 
Why leaving things unfinished messes with your mind

Yale University, January 12 2026 (Medical Xpress)
In a new study, published in the Journal of Experimental Psychology: General, Yale professor of psychology Brian Scholl and lab members explored why humans so badly want to finish what we've started—in matters great and small.
It turns out the brain just doesn't like dangling threads.
The researchers had a hunch that visual clues could help explain the lure of the unfinished. Why is this state of leaving things undone so salient to us? It's an interesting quirk of human nature that science has not previously addressed.
Unfinishedness has been found to decrease work satisfaction, impair sleep, and fuel ruminative thinking patterns. The researchers turned to the visual system. When we see unfinished events, are they somehow prioritized in memory?"
To test their hunch that visual memory plays a role in making unfinishedness feel so sticky, the researchers ran four experiments involving a total of 120 participants who viewed computer animations of simple mazes populated by moving dots or lines.
In several experiments, it seemed that the brain is wired to notice and remember incomplete things better than finished ones. The findings suggest that "unfinishedness" isn't just about motivation or satisfaction. It's built into the way people see and remember the world.

 




Short-term, calorie-restrictive diet improves Crohn’s disease symptoms




 
 




Stanford University, January 13 2026 (News-Medical)

 
There have been few large studies of dietary interventions for IBD, a group of disorders that includes ulcerative colitis and Crohn's disease. Now a Stanford Medicine-led study finds a short-term, calorie-restrictive diet significantly improved symptoms.
Their national, randomized controlled clinical trial found that a short-term, calorie-restrictive diet significantly improved both physical symptoms and biological indicators of mild-to-moderate Crohn's disease.

A chronic condition affecting about a million Americans, Crohn's disease causes inflammation in the digestive tract, leading to symptoms of diarrhea, cramping, abdominal pain and weight loss. Steroids are the only approved therapeutic for mild Crohn's, but their use is limited due to significant side effects, particularly with long-term use.
The study compared the symptoms and biological indicators of patients with mild-to-moderate Crohn's disease as they either followed a fasting mimicking diet or ate their normal diet for three consecutive months. The study enrolled 97 patients across the country, with 65 in the fasting mimicking group and 32 in the control group.
Participants in the fasting mimicking group severely limited their calories for five consecutive days per month, eating between about 700 and 1,100 calories a day. Plant-based meals were provided during the fasting period. For the remainder of the month, the fasting mimicking group ate their normal diet.
At the end of the study, two-thirds of the fasting mimicking group experienced improvement in their symptoms. The researchers found a significant decline in fecal calprotectin, a protein in the stool that indicates gut inflammation, in the fasting mimicking group compared with the control group. Some inflammation-promoting lipid mediators derived from fatty acids also declined in fasting mimicking group participants. Similarly, the immune cells of fasting mimicking group participants produced fewer of several types of inflammatory molecules.


 
Higher daylight exposure improves cognitive performance, study finds
University of Manchester (UK), January 12 2026 (Medical Xpress)
A real world study led by University of Manchester neuroscientists has shown that higher daytime light exposure positively influences different aspects of cognition.



The first study of its kind showed that stable light exposure across a week and uninterrupted exposure during a day had similar effects.
Participants in the study experienced improved subjective sleepiness, the ability to maintain focused attention and 7-10% faster reaction speeds under bright light when compared to recent dim conditions.
Compared with their peers who went to bed later, participants with earlier bedtimes tended to be both more reliably wakeful under bright morning light and sleepy under dimmer evening light.
Being exposed to bright, stable daytime light was linked to enhanced and more sustained attention in a visual search task in which participants were asked to find a specific target on a page.
Higher daytime light exposure and fewer switches between light and dark were linked to improved cognitive performance.
And higher daytime light exposure and earlier estimated bedtimes were also associated with stronger relationships between recent light exposure and subjective sleepiness.
However, neither the time of day nor time awake significantly impacted cognitive performance; the effect of light was stronger than the effect of time of day.

 

Breastfeeding may lower mums’ later life depression/anxiety risks for up to 10 years after pregnancy
University College Dublin (Ireland), January 8 2026 (Eurekalert)


 



Breastfeeding may lower mothers’ later life risks of depression and anxiety for up to 10 years after pregnancy, suggest the findings of a small observational study, published in the open access journal BMJ Open.
The observed associations were apparent for any, exclusive, and cumulative (at least 12  months) breastfeeding, the study shows.
The researchers tracked the breastfeeding behaviour and health of 168 second time mothers who were originally part of the ROLO Longitudinal Birth Cohort Study for 10 years.
 
At the check-ups, the mothers provided information on: whether they had ever breastfed or expressed milk for 1 day or more; total number of weeks of exclusive breastfeeding; total number of weeks of any breastfeeding; and cumulative periods of breastfeeding of less or more than 12 months.
 
The study concludes there may be a protective effect of successful breastfeeding on postpartum depression and anxiety, which in turn lowers the risk of maternal depression and anxiety in the longer term.

The Gary Null Show 1-15-26

HEALTH NEWS
 


<ul>
<li>
Can exercise turn back the clock on your brain? New study says yes
</li>
<li>
Why leaving things unfinished messes with your mind
</li>
<li>
Short-term, calorie-restrictive diet improves Crohn’s disease symptoms
</li>
<li>
Higher daylight exposure improves cognitive performance, study finds
</li>
<li>
Breastfeeding may lower mums’ later life depression/anxiety risks for up to 10 years after pregnancy
</li>
</ul>

The Gary Null Show - 1-14-26

The Gary Null Show 1-13-26

Rediscovering Purpose in the Age of AI

The Gary Null Show 1-12-26

The Rewards of Risk What are you willing to risk?
This is not a rhetorical question. It is one of the most important questions you will ever ask yourself, because your answer determines the size, texture, and vitality of your life.

The Gary Null Show - 1-9-26

Choosing Not to Fit In
When I first came to New York, I worked briefly at a Fortune 500 company. It did not take long for me to realize that I could never work in a large corporation. I did not fit in—and I did not want to.
I would rather take a chance, even risk unemployment, than surrender my autonomy. I do not fit comfortably in corporate America, government, industry, or even most movements. I may believe in a movement’s goals, but I rarely trust its leadership. Too often, ego replaces balance.
That clarity has shaped my life.

The Gary Null Show - 1-8-26

The Gary Null Show - 1-7-26

Positive Defiance Creates the Freedom to Be Yourself

The Gary Null Show - 1.6.26

Your Daily Cup of Tea Could Help Fight Heart Disease, Cancer, Aging, and More

The Gary Null Show - 1-5-26

Gary's update to Overcoming The Dark Side

The Gary Null Show - 1.2.26.

HEALTH NEWS
 

<ul>
<li>
Naturally occurring molecule shown to restore memory function in Alzheimer's models
</li>
<li>
Exercise helps breast cancer survivors maintain bone density
</li>
<li>
Too Much Night Light? It Could Be Hurting Your Heart
</li>
<li>
Curcumin inhibits pituitary tumor cell proliferation, induces apoptosis
</li>
<li>
How certain gut bacteria drive multiple sclerosis
</li>
</ul>

The Gary Null Show - 12-31-25

Alzheimer's disease can be reversed in animal models to achieve full neurological recovery.

The Gary Null Show - 12.29.25.

Scientists map how cinnamon’s bioactives interact with cancer signaling

The Gary Null Show - 12-26-25

Manifesting a beautiful life does not begin by acquiring more. It begins by appreciating
what already exists. Gary Null, PhD

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