…

The a16z Show

…

Andreessen Horowitz

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

#1000

Who Grades the AI Models? | Ben Horowitz & Rayan Krishnan

a16z’s Erik Torenberg, Ben Horowitz, and Jennifer Li sit down with Vals founder and CEO Ra... more

17 hrs Ago

39 MINS

39:45

17 hrs Ago

#999

OpenAI Researchers on the Future of Mathematical Reasoning

a16z Infra Partner Lisha Li sits down with OpenAI mathematicians Mehtaab Sawhney and Mark ... more

Yesterday

1 HR 05 MINS

1:05:15

Yesterday

#998

Can Open Source Keep AI Power From Concentrating?

MTS host Sophia Dew visits the Open Source AI Summit in San Francisco to ask researchers a... more

07 Sep 2026

08 MINS

08:05

07 Sep 2026

#997

Your AI Doctor Is Coming | Julie Yoo

a16z General Partner Julie Yoo joins MTS host Sophia Dew to explain why she believes healt... more

06 Sep 2026

27 MINS

27:30

06 Sep 2026

#996

Aaron Levie on Why Open AI Wins

Box co-founder and CEO Aaron Levie joins MTS hosts Theo Jaffee and Sofia Puccini to make t... more

05 Sep 2026

31 MINS

31:05

05 Sep 2026

#995

Fei Fei Li: The Race to Build World Models For AI

World Labs co-founders Fei-Fei Li, Justin Johnson, and Ben Mildenhall join a16z General Pa... more

04 Sep 2026

44 MINS

44:36

04 Sep 2026

#994

The $100B Niches Hiding Inside Payments

Erik Torenberg is joined by a16z General Partner Alex Rampell and Affirm Co-Founder and CE... more

03 Sep 2026

1 HR 00 MINS

1:00:39

03 Sep 2026

#993

Inside Moderna’s Personalized Cancer Vaccine

a16z General Partner Jorge Conde sits down with Moderna CEO Stéphane Bancel to discuss a m... more

02 Sep 2026

40 MINS

40:10

02 Sep 2026

#992

Daniel Litt: The Mathematician's Guide to AI

a16z’s Lisha Li sits down with Daniel Litt, Assistant Professor of Mathematics at the Univ... more

01 Sep 2026

1 HR 03 MINS

1:03:49

01 Sep 2026

#991

Gavin Baker: Why AI Demand Is Outrunning Compute Supply

a16z’s David George sits down with Gavin Baker to unpack the state of the AI boom, why dem... more

31 Aug 2026

1 HR 15 MINS

1:15:11

31 Aug 2026

#990

Why a16z Launched the Machine Age Fund | Jen Kha

a16z Managing Partner and Head of Global Partnerships Jen Kha joins MTS hosts Theo Jaffee ... more

30 Aug 2026

24 MINS

24:37

30 Aug 2026

#989

Why 1,200 AI Agents Started Working Together | Ryan Greenblatt

Ryan Greenblatt, Chief Scientist at Redwood Research, joins MTS host Theo Jaffee to unpack... more

29 Aug 2026

34 MINS

34:15

29 Aug 2026

#988

The Infrastructure Behind the Machine Age

Ben Horowitz, Martin Casado, Raghu Raghuram, and Erik Torenberg discuss the launch of a16z... more

28 Aug 2026

55 MINS

55:02

28 Aug 2026

#987

Inside Cursor: The Anatomy of a Generational Startup

a16z General Partners Martin Casado, Sarah Wang, and Matt Bornstein unpack the story of Cu... more

27 Aug 2026

39 MINS

39:29

27 Aug 2026

#986

The State of AI: Macro, Apps, and Consumer

Anish Acharya joins Jen Kha to break down the next frontier of AI, from the evolving model... more

26 Aug 2026

37 MINS

37:14

26 Aug 2026

#985

The New Economics of AI | Martin Casado & Steven Sinofsky

a16z General Partners Martin Casado and Erik Torenberg are joined by Board Partner Steven ... more

25 Aug 2026

1 HR 03 MINS

1:03:32

25 Aug 2026

#984

Why Medical AI Needs a Referee | Protege's Engy Ziedan

Daisy Wolf and Eva Steinman are joined by Engy Ziedan, co-founder and Chief Scientific Off... more

24 Aug 2026

35 MINS

35:21

24 Aug 2026

#983

Martin Casado on Where the Value Is Going in AI

Martin Casado joins MTS hosts Theo Jaffee and Sophia Dew to unpack where value is actually... more

22 Aug 2026

42 MINS

42:01

22 Aug 2026

#982

Microsoft's Deputy CISO on Securing AI Agents

a16z's Joel De La Garza is joined by Aaron Zollman, Deputy CISO at Microsoft Gaming, to di... more

21 Aug 2026

25 MINS

25:15