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Talk Python To Me

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Michael Kennedy

Talk Python to Me is a weekly podcast hosted by developer and entrepreneur Michael Kennedy. We dive deep into the popular packages and software developers, data scientists, and incredible hobbyists doing amazing things with Python. If you're new to Python, you'll quickly learn the ins and outs of the community by hearing from the leaders. And if you've been Pythoning for years, you'll learn about your favorite packages and the hot new ones coming out of open source.

#551

#552: Astral joins OpenAI

OpenAI just acquired Astral, the company behind uv, Ruff, and ty. And if your first though... more

17 Jun 2026

1 HR 05 MINS

1:05:08

17 Jun 2026

#550

#551: Stroll Down Startup Lane - 2026

If you've ever been to PyCon, you know one of the best parts of the expo hall is Startup R... more

11 Jun 2026

1 HR 48 MINS

1:48:54

11 Jun 2026

#549

#550: AI Contributions and Maintainer Load in Open Source

You wake up, brew the coffee, open GitHub, and there it is. Another pull request on your o... more

30 May 2026

1 HR 02 MINS

1:02:42

30 May 2026

#548

#549: Great Docs

Your documentation has two audiences now - humans reading the rendered HTML, and AI agents... more

25 May 2026

1 HR 07 MINS

1:07:00

25 May 2026

#547

#548: Event Sourcing Design Pattern

What if your database worked more like Git? Every change captured as an immutable event yo... more

11 May 2026

1 HR 08 MINS

1:08:49

11 May 2026

#546

#547: Parallel Python at Anyscale with Ray

When OpenAI trained GPT-3, they didn't roll their own orchestration layer. They used Ray, ... more

06 May 2026

59 MINS

59:16

06 May 2026

#545

#546: Self hosting apps for Python people

The cloud is convenient until it isn't. You upload your photos, sync your contacts, click ... more

27 Apr 2026

1 HR 03 MINS

1:03:12

27 Apr 2026

#544

#545: OWASP Top 10 (2025 List) for Python Devs

The OWASP Top 10 just got a fresh update, and there are some big changes: supply chain att... more

16 Apr 2026

1 HR 06 MINS

1:06:03

16 Apr 2026

#543

#544: Wheel Next + Packaging PEPs

When you pip install a package with compiled code, the wheel you get is built for CPU feat... more

10 Apr 2026

1 HR 11 MINS

1:11:17

10 Apr 2026

#542

#543: Deep Agents: LangChain's SDK for Agents That Plan and Delegate

When you type a question into ChatGPT, the model only has what you typed to work with. But... more

01 Apr 2026

1 HR 03 MINS

1:03:53

01 Apr 2026

#541

#542: Zensical - a modern static site generator

If you've built documentation in the Python ecosystem, chances are you've used Martin Dona... more

25 Mar 2026

1 HR 04 MINS

1:04:03

25 Mar 2026

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