The a16z Show podcast

…

The a16z Show

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

 

#1000

What Happens When Everyone Has a Health Expert in Their Pocket? | OpenAI’s Karan Singhal

More than 300 million people use ChatGPT for health and wellness questions each week. Open... more

Yesterday

55 MINS

55:50

Yesterday


#999

What Happens When Al Agents Can Spend Your Money?

Why hasn't AI transformed everyday work as quickly as coding? Town CEO Jean-Denis Greze ar... more

19 Oct 2026

1 HR 02 MINS

1:02:46

19 Oct 2026


#998

Why Real-World AI Is Harder Than the Benchmark | EliseAI’s Mario Martone

What changes when an AI mistake doesn’t just hurt a benchmark score, but affects someone’s... more

18 Oct 2026

24 MINS

24:25

18 Oct 2026


#997

Why AI Could Finally Fix Healthcare Access | Zocdoc CEO Oliver Kharraz

Why is booking a doctor's appointment still so difficult, and can AI finally change that? ... more

17 Oct 2026

34 MINS

34:56

17 Oct 2026


#996

AI Can Write the Code. Can It Run the System? | Grepr CEO Jad Naous

a16z General Partner Martin Casado sits down with Grepr CEO Jad Naous to ask what comes af... more

16 Oct 2026

1 HR 00 MINS

1:00:02

16 Oct 2026


#995

When AI Agents Start Spending Your Money | Alex Rampell & Terry Angelos

a16z General Partner Alex Rampell sits down with VGS Executive Board Member, Terry Angelos... more

15 Oct 2026

51 MINS

51:29

15 Oct 2026


#994

Can Open Models Keep Up With the AI Frontier? | Nathan Lambert

a16z Partner Lisha Li sits down with AI researcher and Trillium founder Nathan Lambert to ... more

14 Oct 2026

59 MINS

59:54

14 Oct 2026


#993

Can AI Break Cryptography? What the Experts Actually Think

Could AI break the cryptography protecting everything from crypto wallets and banking to p... more

13 Oct 2026

42 MINS

42:11

13 Oct 2026


#992

The Race to Recursive Self-Improving AI

a16z General Partner Martin Casado sits down with MakerMaker.AI co-founders Dhaval Adjodah... more

12 Oct 2026

33 MINS

33:27

12 Oct 2026


#991

Nick Bostrom: How Should We Navigate Superintelligence?

Nick Bostrom joins Theo Jaffee and Sofia Puccini on MTS to revisit the ideas about superin... more

11 Oct 2026

53 MINS

53:56

11 Oct 2026


#990

What Makes a Great Entrepreneur? | Ben Horowitz on Vintage x Vintage

a16z co-founder and General Partner Ben Horowitz joins James Norman on the inaugural episo... more

10 Oct 2026

51 MINS

51:37

10 Oct 2026


#989

Chips, Memory, and Power | Pat Gelsinger

a16z's Raghu Raghuram and Guido Appenzeller sit down with Playground Global General Partne... more

09 Oct 2026

54 MINS

54:15

09 Oct 2026


#988

Building the Cloud for an Agentic World | AWS CEO Matt Garman

a16z’s Raghu Raghuram sits down with AWS CEO Matt Garman to discuss how AI is reshaping th... more

08 Oct 2026

56 MINS

56:17

08 Oct 2026


#987

How Valon Rebuilt a $13 Trillion Industry From Scratch

a16z General Partner Angela Strange sits down with Valon’s Andrew Wang and Linda Du to unp... more

07 Oct 2026

40 MINS

40:33

07 Oct 2026


#986

Building Defense for the Agentic Era: Kevin Mandia

a16z General Partner David George sits down with Armadin founder and CEO Kevin Mandia to d... more

06 Oct 2026

49 MINS

49:09

06 Oct 2026


#985

The Top 100 Consumer AI Apps: Who’s Actually Paying?

a16z Editorial Partner Elena Burger sits down with investing partners Olivia Moore and Jos... more

05 Oct 2026

51 MINS

51:04

05 Oct 2026


#984

David George & Jack Altman on AI, Autonomy, and the Next $25 Trillion

a16z General Partner David George joins Jack Altman on Uncapped to make the case that many... more

04 Oct 2026

55 MINS

55:03

04 Oct 2026


#983

Beyond the God Model | Alex Atallah & Amjad Masad

A16z’s Erik Torenberg sits down with OpenRouter’s Alex Atallah and Replit founder and CEO ... more

03 Oct 2026

48 MINS

48:17

03 Oct 2026


#982

Why AI Agents Can Beat the Incumbents

a16z’s Seema Amble and Elena Burger sit down with Lio co-founder and CEO Vladimir Keil to ... more

02 Oct 2026

59 MINS

59:48

02 Oct 2026


#981

Rebuilding the Internet for Privacy | Barrett Lyon on DoxxNet

a16z’s Joel de la Garza sits down with DoxxNet founder Barrett Lyon to discuss what it wou... more

01 Oct 2026

45 MINS

45:23

01 Oct 2026