The a16z Show podcast

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The a16z Show

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

 

#1000

Scott Kupor on Building a16z and Rebuilding the Federal Workforce

Scott Kupor helped build a16z from three people into a firm with hundreds of employees. No... more

Yesterday

56 MINS

56:46

Yesterday


#999

The Health Interventions Actually Worth Your Time | Justin Mares

Health advice has become an endless stream of supplements, diets, wearables, and biohacks.... more

08 Nov 2026

26 MINS

26:26

08 Nov 2026


#998

Mark Hyman’s Guide to Living Longer and Staying Strong

What actually matters if you want to stay healthy as you age? Dr. Mark Hyman argues it isn... more

07 Nov 2026

30 MINS

30:56

07 Nov 2026


#997

Inside Salesforce’s $100 Billion M&A Playbook | John Somorjai

What makes a startup worth acquiring when software has never been easier to build? Salesfo... more

06 Nov 2026

49 MINS

49:00

06 Nov 2026


#996

The New CFO: How AI Is Rewriting the Finance Function | Figma CFO Praveer Melwani

AI is moving finance from reconciling what happened last month to helping decide what the ... more

05 Nov 2026

50 MINS

50:57

05 Nov 2026


#995

The New AI Agents That Shop, Plan, and Gossip

Will we have one AI assistant that does everything, or an entire network of agents that kn... more

04 Nov 2026

51 MINS

51:28

04 Nov 2026


#994

Andrew Huberman’s Three Rules for Better Health and Focus

If you could do only three things for your health, what should they be? Andrew Huberman’s ... more

03 Nov 2026

49 MINS

49:07

03 Nov 2026


#993

The Robots Already Working in American Factories | Tutor Intelligence

What does it take to build robots that can actually work in factories and warehouses? Tuto... more

02 Nov 2026

46 MINS

46:05

02 Nov 2026


#992

How Bending Spoons Built a $20 Billion Compounder | Luca Ferrari

Can relentless optimization create as much value as breakthrough invention? Bending Spoons... more

01 Nov 2026

44 MINS

44:20

01 Nov 2026


#991

Can AI Fix Professional Networking? | Inside Cosign

What if finding your next job, co-founder, or collaborator depended less on a resume and m... more

31 Oct 2026

25 MINS

25:21

31 Oct 2026


#990

Why AI Could Turn Small Law Firms Into Billion-Dollar Businesses

What happens when AI makes legal work cheap enough to take cases lawyers couldn't afford t... more

30 Oct 2026

53 MINS

53:14

30 Oct 2026


#989

The Startups Rebuilding American Industry | The AD50

America’s defense, energy, manufacturing, and robotics booms are increasingly becoming one... more

29 Oct 2026

50 MINS

50:21

29 Oct 2026


#988

Mark Cuban on Why AI Could Turn Solo Founders Into Trillionaires

Mark Cuban thinks AI could transform healthcare, but it won’t fix opaque prices and broken... more

28 Oct 2026

1 HR 01 MINS

1:01:26

28 Oct 2026


#987

Reinventing School for the AI Era | Joe Liemandt, Gagan Biyani & Erik Torenberg

What should school look like if AI can help students learn dramatically faster? Alpha Scho... more

27 Oct 2026

56 MINS

56:52

27 Oct 2026


#986

OpenAI: When AI Agents Use Computers Faster Than You

AI agents are approaching a point where they can use computers faster than expert humans, ... more

26 Oct 2026

45 MINS

45:19

26 Oct 2026


#985

The New Startup Playbook | Box CEO Aaron Levie

Can a 10-person startup outperform a company with hundreds of employees? Box CEO Aaron Lev... more

25 Oct 2026

34 MINS

34:24

25 Oct 2026


#984

What It Takes to Win as a Founder | Ben Horowitz

What does it take to build a company when AI is changing the rules this quickly? Ben Horow... more

24 Oct 2026

41 MINS

41:52

24 Oct 2026


#983

Amazon CEO Andy Jassy on the $220 Billion AI Buildout

Amazon expects to spend roughly $220 billion in CapEx in 2026, yet CEO Andy Jassy says the... more

23 Oct 2026

1 HR 01 MINS

1:01:21

23 Oct 2026


#982

The Frontier Ideas a16z Wants to Fund | Marc Andreessen, Ben Horowitz & Chris Dixon

a16z is expanding a16z crypto into a16z Frontier, a broader mandate to back founders build... more

22 Oct 2026

1 HR 01 MINS

1:01:00

22 Oct 2026


#981

The Missing Infrastructure for AI Agents: Documents | Reducto’s Adit Abraham

AI agents can reason over enormous amounts of information, but much of the world’s actual ... more

21 Oct 2026

38 MINS

38:17

21 Oct 2026