a16z Podcast podcast

a16z Podcast

The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

 

#833

Marc Andreessen: Can Tech Finally Fix Healthcare?

Healthcare is a $4 trillion industry, making up nearly a fifth of the U.S. economy—but despite having some of the best doctors and advanced technology, the system often delivers poor outcomes at skyrocketing costs. Why is this the case, and what will it take to fix it? In this episode, a16z cofounder Marc Andreessen and General Partners Vijay Pande and Julie Yoo tackle some of the biggest questions shaping the future of healthcare: ---Is the solution to our healthcare crisis a policy, technology, or competition problem? ---Will AI and technology transform the industry, or are regulatory and structural barriers too entrenched? ---Who will crack the code—healthcare incumbents, tech giants, or AI-native startups? From chronic care to cost curves, from disruptive technologies to shifting patient agency, this conversation offers an unfiltered look at what’s broken in the healthcare system and how it might finally change. Resources:  Find Marc on X: [https://x.com/pmarca] (https://x.com/pmarca) Find Vijay on X: [https://x.com/vijaypande] (https://x.com/vijaypande) Find Julie on X: [https://x.com/julesyoo] (https://x.com/julesyoo) [The Biggest Company in the World] (https://a16z.com/the-biggest-company-in-the-world/) [Why Will Healthcare be the Industry that Benefits Most from AI?] (https://a16z.com/why-will-healthcare-be-the-industry-that-benefits-the-most-from-ai/) [Grand Challenges in Healthcare AI with Vijay Pande and Julie Yoo] (https://a16z.com/podcast/grand-challenges-in-healthcare-ai-with-vijay-pande-and-julie-yoo/) Stay Updated:  Let us know what you think: [https://ratethispodcast.com/a16z] (https://ratethispodcast.com/a16z) Find a16z on Twitter: [https://twitter.com/a16z] (https://twitter.com/a16z) Find a16z on LinkedIn: [https://www.linkedin.com/company/a16z] (https://www.linkedin.com/company/a16z) Subscribe on your favorite podcast app: [https://a16z.simplecast.com/] (https://a16z.simplecast.com/) Follow our host: [https://twitter.com/stephsmithio] (https://twitter.com/stephsmithio) Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. ... Read more

6 hrs Ago

32 MINS

32:33

6 hrs Ago


#832

Building Substack: Reinventing Culture through Subscriptions

In this episode, Substack cofounder and CEO Chris Best joins a16z General Partner Andrew Chen to discuss the origins and evolution of Substack, a platform redefining media and empowering creators to connect directly with their audiences. They dive into how Substack’s early days led to over 3 million paid subscribers, why creators are moving away from traditional platforms to establish direct connections with their audiences, and how the future of media in the AI era is reshaping opportunities for writers, podcasters, and video creators. From Chris’s lessons scaling Kik Messaging to Substack’s profound impact on the creator economy, this conversation shares insights on building platforms, culture, and opportunity in the modern era.   Resources:  Find Chris on Substack: [https://cb.substack.com/] (https://cb.substack.com/) Find Andrew Chen on Substack: [https://andrewchen.substack.com/] (https://andrewchen.substack.com/)   Stay Updated:  Let us know what you think: [https://ratethispodcast.com/a16z] (https://ratethispodcast.com/a16z) Find a16z on Twitter: [https://twitter.com/a16z] (https://twitter.com/a16z) Find a16z on LinkedIn: [https://www.linkedin.com/company/a16z] (https://www.linkedin.com/company/a16z) Subscribe on your favorite podcast app: [https://a16z.simplecast.com/] (https://a16z.simplecast.com/) Follow our host: [https://twitter.com/stephsmithio] (https://twitter.com/stephsmithio) Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. ... Read more

09 Jan 2025

36 MINS

36:45

09 Jan 2025


#831

Crypto Trends for 2025: Stablecoins, App Stores, UX, and More

with @sambroner @meigga @darenmatsuoka @jneu_net @chrislyons and @rhhackett @smc90 Welcome to our special end-of-year episodes -- which also [look ahead to 2025] (https://a16zcrypto.com/posts/article/big-ideas-crypto-2025/) --  covering our [annual Big Ideas lists] (https://a16zcrypto.com/posts/tags/annual-big-ideas) , where various a16z crypto team members share what they are personally excited about. (You can see the firmwide list, also including all the trends of the crypto team,   [here] (https://a16z.com/big-ideas-in-tech-2025/) .) This episode is part 1 of 2 -- but you don't have to listen to them in any particular order -- covering the trends and themes of: ---stablecoins, payments, and where the early adopters will come from; ---app store distribution, curation, and discovery; ---where the next crypto users will come from, turning passive holders into active users; ---how builders improve, and better choose, infrastructure; and ---simplifying user experience.  Covering each of these -- and coming from the investing, go-to-market, data science, research, and media teams are:  Sam Broner, Maggie Hsu, Daren Matsuoka, Joachim Neu, and Chris Lyons; in conversation with hosts Sonal Chokshi and Robert Hackett. (Stay tuned until the end for some of our meta-commentary.)  These are just 5 of the 14 trends we shared; you can check out the full list at a16zcrypto.com/bigideas. Also be sure to check out part 2, which covers all the trends at the intersection of crypto and AI.  As a reminder, none of the content is investment, business, legal, or tax advice; please see a16z.com/disclosures for more important information -- including a link to a list of our investments. ... Read more

03 Jan 2025

34 MINS

34:54

03 Jan 2025


#830

Super Staffing Healthcare, Codifying Compliance, & Scaling Services

As we prepare to step into 2025, the possibilities for applied AI are reshaping industries in profound ways.  In this episode, a16z General Partners Julie Yoo and Angela Strange, and Partner Joe Schmidt, dive into the transformative power of AI across healthcare, fintech, and traditional service sectors. We explore: ---Super Staffing for Healthcare: How AI can address critical clinical labor shortages and augment care delivery at scale. ---Regulation Becomes Code: The potential for AI to simplify and streamline compliance, making systems safer and more efficient. ---Romanticizing Inorganic Growth: The opportunity for AI-powered startups to redefine service industries through workflow automation and strategic acquisition. With insights from a16z’s Bio + Health, Fintech, and Apps teams, this episode unpacks the ideas that will revolutionize traditional systems and unlock opportunities in 2025. Check out the full 50 Big Ideas for 2025 at [a16z.com/bigideas] (http://a16z.com/bigideas) .   Resources:  Find Angela on X: [https://x.com/astrange] (https://x.com/astrange) Find Julie on X: [https://x.com/julesyoo] (https://x.com/julesyoo) Find Joe on X: [https://x.com/joeschmidtiv] (https://x.com/joeschmidtiv) Link to article 'The Messy Inbox Problem: Wedge Strategies in AI Apps': [https://a16z.com/the-messy-inbox-problem-ai-apps-wedge-strategies] (https://a16z.com/the-messy-inbox-problem-ai-apps-wedge-strategies)   Stay Updated:  Let us know what you think: [https://ratethispodcast.com/a16z] (https://ratethispodcast.com/a16z) Find a16z on Twitter: [https://twitter.com/a16z] (https://twitter.com/a16z) Find a16z on LinkedIn: [https://www.linkedin.com/company/a16z] (https://www.linkedin.com/company/a16z) Subscribe on your favorite podcast app: [https://a16z.simplecast.com/] (https://a16z.simplecast.com/) Follow our host: [https://twitter.com/stephsmithio] (https://twitter.com/stephsmithio) Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. ... Read more

30 Dec 2024

52 MINS

52:09

30 Dec 2024


#829

The Race for AI—Search, National Infrastructure, & On-Device AI

The AI race is on, and 2025 could be its most transformative year yet. In this episode, a16z General Partners Anjney Midha and Jennifer Li, and Partner Alex Immerman dive into the trends reshaping AI and its impact on search, infrastructure, and devices. We explore: ---How AI-native tools like ChatGPT and Perplexity are challenging Google’s search dominance. ---The rise of infrastructure independence as governments prioritize compute, energy, and data. ---The future of smaller, on-device AI models driving privacy, performance, and new consumer applications. With insights from a16z’s Growth and Infrastructure teams, this episode unpacks the forces driving AI innovation—and the opportunities founders and nations could seize to lead in the next wave of technology. Stay tuned for more in this four-part series, and explore the full 50 Big Ideas for 2025 at [a16z.com/bigideas] (http://a16z.com/bigideas) . Resources:  Find Alex on X: [https://x.com/aleximm] (https://x.com/aleximm) FInd Anjney on X: [https://x.com/AnjneyMidha] (https://x.com/AnjneyMidha) FInd Jennifer on X: [https://x.com/JenniferHli] (https://x.com/JenniferHli) Stay Updated:  Let us know what you think: [https://ratethispodcast.com/a16z] (https://ratethispodcast.com/a16z) Find a16z on Twitter: [https://twitter.com/a16z] (https://twitter.com/a16z) Find a16z on LinkedIn: [https://www.linkedin.com/company/a16z] (https://www.linkedin.com/company/a16z) Subscribe on your favorite podcast app: [https://a16z.simplecast.com/] (https://a16z.simplecast.com/) Follow our host: [https://twitter.com/stephsmithio] (https://twitter.com/stephsmithio) Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. ... Read more

25 Dec 2024

42 MINS

42:45

25 Dec 2024


#828

Jobs of the Future, Harnessing Earth Observation, & Gaming Tech Advances

As 2025 begins, industries are evolving at unprecedented speed: robots are revolutionizing manufacturing, terabytes of earth observation data are driving new possibilities, and gaming technology is transforming how we design, train, and innovate across sectors. In this episode, a16z General Partner Erin Price-Wright, Engineering Fellow Millen Anand, and Partner Troy Kirwin discuss the trends reshaping the future of hardware, software, and beyond. We explore: ---How robots and full-stack engineers are driving the next industrial renaissance. ---The explosion of Earth observation data and its potential to revolutionize industries. ---How gaming technology is moving beyond entertainment to reshape training, design, and more. This is just the beginning of our four-part series on 50 Big Ideas for 2025—don’t miss the full list at [a16z.com/bigideas] (http://a16z.com/bigideas) . Resources:  Find Erin on X: [https://x.com/espricewright] () Find Millen on LinkedIn: [https://www.linkedin.com/in/millen-anand/] () Find Troy on X: [https://x.com/tkexpress11] (https://x.com/tkexpress11) Stay Updated:  Let us know what you think: [https://ratethispodcast.com/a16z] (https://ratethispodcast.com/a16z) Find a16z on Twitter: [https://twitter.com/a16z] (https://twitter.com/a16z) Find a16z on LinkedIn: [https://www.linkedin.com/company/a16z] (https://www.linkedin.com/company/a16z) Subscribe on your favorite podcast app: [https://a16z.simplecast.com/] (https://a16z.simplecast.com/) Follow our host: [https://twitter.com/stephsmithio] (https://twitter.com/stephsmithio) Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. ... Read more

20 Dec 2024

41 MINS

41:59

20 Dec 2024


#827

Scaling Shopify: Tobias Lütke and Ben Horowitz on Building a Global Giant

In this episode of Web3 with a16z, Shopify CEO and cofounder Tobias Lütke joins a16z cofounder Ben Horowitz for a conversation recorded live at the a16z crypto Founders Summit. Together, they explore what it takes to build a breakout startup in a competitive market, the changing landscape of retail, and how to drive workplace change while navigating corporate culture and calls for activism. Tobias shares the story behind Shopify's growth from a snowboarding store to a global ecommerce platform serving millions of merchants, discusses the moral imperative of creating great software, and offers insights on leadership, innovation, and embracing negativity as a tool for progress. The episode also touches on the intersection of AI and crypto, the power of decentralization, and the next wave of technologies reshaping business and commerce.   Resources: Find Ben on X: [https://x.com/bhorowitz] (https://x.com/bhorowitz) Find Toni on X: [ https://x.com/tobi] (https://x.com/tob)   Stay Updated:  Let us know what you think: [https://ratethispodcast.com/a16z] (https://ratethispodcast.com/a16z) Find a16z on Twitter: [https://twitter.com/a16z] (https://twitter.com/a16z) Find a16z on LinkedIn: [https://www.linkedin.com/company/a16z] (https://www.linkedin.com/company/a16z) Subscribe on your favorite podcast app: [https://a16z.simplecast.com/] (https://a16z.simplecast.com/) Follow our host: [https://twitter.com/stephsmithio] (https://twitter.com/stephsmithio) Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. ... Read more

16 Dec 2024

45 MINS

45:26

16 Dec 2024


#826

How AI is Transforming Labor Markets

Did you know the U.S. nurse labor market is over $600 billion annually, but the dedicated software market for nurses is almost zero? In this episode General Partners Alex Rampell, David Haber, and Angela Strange discuss how AI is revolutionizing labor by automating tasks traditionally done by humans. They’ll trace the evolution of cloud eras — from the original to financial services-enabled to the current AI-enabled outcomes era — showcasing how AI is creating unprecedented opportunities, allowing startups to outpace incumbents. They also explore how this shift will reshape industries, where we are in the adoption curve and what companies need to succeed, and the gaps where the a16z Enterprise team would love to see more innovation. Resources: ---AI Turns Capital to Labor:  [ https://a16z.com/ai-turns-capital-to-labor/] (https://a16z.com/ai-turns-capital-to-labor/) ---The Messy Inbox Problem: [https://a16z.com/the-messy-inbox-problem-ai-apps-wedge-strategies/] (https://a16z.com/the-messy-inbox-problem-ai-apps-wedge-strategies/) ---Vertical SaaS: Now with AI Inside: [https://a16z.com/vertical-saas-now-with-ai-inside/] (https://a16z.com/vertical-saas-now-with-ai-inside/) ---BarbAIrians at the Gate: The Financial Opportunity of AI: [https://a16z.com/financial-opportunity-of-ai/] (https://a16z.com/financial-opportunity-of-ai/) Stay Updated: ---Let us know what you think: [https://ratethispodcast.com/a16z] (https://ratethispodcast.com/a16z) ---Find a16z on Twitter: [https://twitter.com/a16z] (https://twitter.com/a16z) ---Find a16z on LinkedIn: [https://www.linkedin.com/company/a16z] (https://www.linkedin.com/company/a16z) ---Subscribe on your favorite podcast app: [https://a16z.simplecast.com/] (https://a16z.simplecast.com/) ---Follow our host: [https://twitter.com/stephsmithio] (https://twitter.com/stephsmithio) Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.a   ... Read more

11 Dec 2024

44 MINS

44:38

11 Dec 2024


#825

Fixing Education in America: What's Stopping Us?

Over half of Americans live in childcare deserts, while 90% of brain development happens before the age of five. All the while, education and childcare remain among the most resistant sectors to technological change. Billions of dollars have been spent, but outcomes continue to lag. Why? In this episode, we dive into the systemic issues—misaligned incentives, political resistance, and the lack of a shared vision around the purchase of an education. We also explore how technology and entrepreneurial innovation may be shifting the tide. You’ll hear from Anurupa Ganguly (Prisms), Chris Bennett (Wonderschool), Anna Edwards (Whiteboard Advisors), and a16z General Partner Jeff Jordan discuss the criticality of early childhood education, how public-private partnerships are required for scale, and how we can engage risk-averse decision-makers.  Listen to learn how the next generation can reclaim the American dream.   Resources:  Find Jeff on Twitter: [https://x.com/jeff_jordan] (https://x.com/jeff_jordan) Find Chris on Twitter: [https://x.com/8ennett] (https://x.com/8ennett) Find Anna on LinkedIn: [https://www.linkedin.com/in/annakimseyedwards/] (https://www.linkedin.com/in/annakimseyedwards/) Find Anurupa on Twitter: [https://x.com/aganguly26] (https://x.com/aganguly26)   Stay Updated:  Let us know what you think: [https://ratethispodcast.com/a16z] (https://ratethispodcast.com/a16z) Find a16z on Twitter: [https://twitter.com/a16z] (https://twitter.com/a16z) Find a16z on LinkedIn: [https://www.linkedin.com/company/a16z] (https://www.linkedin.com/company/a16z) Subscribe on your favorite podcast app: [https://a16z.simplecast.com/] (https://a16z.simplecast.com/) Follow our host: [https://twitter.com/stephsmithio] (https://twitter.com/stephsmithio) Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. ... Read more

06 Dec 2024

40 MINS

40:39

06 Dec 2024


#824

Prediction Markets and Beyond

This episode was originally published on our sister podcast, web3 with a16z. If you’re excited about the next generation of the internet, check out the show: [https://link.chtbl.com/hrr_h-XC] (https://link.chtbl.com/hrr_h-XC) We've heard a lot about the premise and the promise of prediction markets for a long time, but they finally hit the main stage with the most recent election. So what worked (and didn't) this time? Are they really better than pollsters, is polling dead?  So in this conversation, we tease apart the hype from the reality of prediction markets, from the recent election to market foundations... going more deeply into the how, why, and where these markets work. We also discuss the design challenges and opportunities (including implications for builders throughout). And we also cover other information aggregation mechanisms -- from peer prediction to others -- given that prediction markets are part of a broader category of information-elicitation and information-aggregation mechanisms. Where do domain experts, superforecasters, pollsters, and journalists come in (and out)? Where do (and don't) blockchain and crypto technologies come in -- and what specific features (decentralization, transparency, real-time, open source, etc.) matter most, and in what contexts?  Finally, we discuss applications for prediction and decision markets -- things we could do right away to in the near-future to sci-fi -- touching on trends like futarchy, AI entering the market, DeSci, and more.   Our special expert guests are Alex Taborrok, professor of economics at George Mason University and Chair in Economics at the Mercatus Center; and Scott Duke Kominers, research partner at a16z crypto, and professor at Harvard Business School  -- both in conversation with Sonal Chokshi.  As a reminder: None of the following should be taken as business, investment, legal, or tax advice; please see a16z.com/disclosures for more important information.    Resources:(from links to research mentioned to more on the topics discussed) --- [The Use of Knowledge in Society] (https://www.econlib.org/library/Essays/hykKnw.html) by Friedrich Hayek (American Economic Review, 1945) --- [Everything is priced in] (https://www.reddit.com/r/wallstreetbets/comments/eberem/everything_is_priced_in/) by rsd99 (r/wallstreetbets, 2019) --- [Idea Futures (aka prediction markets, information markets)] (https://mason.gmu.edu/~rhanson/ideafutures.html) by Robin Hanson (1996) --- [Auctions: The Social Construction of Value] (https://www.ucpress.edu/books/auctions/paper)   by Charles Smith --- [Social value of public information] (https://people.duke.edu/~qc2/BA532/2002%20AER%20Morris%20and%20Shin.pdf) by Stephen Morris and Hyun Song Shin (American Economic Review, December 2002) --- [Using prediction markets to estimate the reproducibility of scientific research] (https://www.pnas.org/doi/full/10.1073/pnas.1516179112) by Anna Dreber, Thomas Pfeiffer, Johan Almenberg, Siri Isaksson, Brad Wilson, Yiling Chen, Brian Nosek, and Magnus Johannesson (Proceedings of the National Academy of Sciences (November 2015) --- [A solution to the single-question crowd wisdom problem] (https://www.nature.com/articles/nature21054) by Dražen Prelec, Sebastian Seung, and John McCoy (Nature, January 2017) --- [Targeting high ability entrepreneurs using community information: Mechanism design in the field] (https://www.hbs.edu/ris/Publication%20Files/Targeting_Entrepreneurs_AER2022_64933cef-316a-437f-8ca4-885d870b2ba1.pdf) by Reshmaan Hussam, Natalia Rigol, and Benjamin Roth (American Economic Review, March 2022) --- [Information aggregation mechanisms: concept, design, and implementation for a sales forecasting problem] (https://www.eecs.harvard.edu/cs286r/courses/fall12/papers/ms020408.pdf) by Charles Plott and Kay-Yut Chen, Hewlett Packard Laboratories (March 2002) --- [If I had a million] (https://www.overcomingbias.com/p/if-i-had-a-millhtml) [on deciding to dump the CEO or not] by Robin Hanson (2008) --- [Futarchy: Vote values, but bet beliefs] (https://mason.gmu.edu/~rhanson/futarchy.html) by Robin Hanson (2013) --- [From prediction markets to info finance] (https://vitalik.eth.limo/general/2024/11/09/infofinance.html) by Vitalik Buterin (November 2024) --- [Composability is innovation] (https://a16zcrypto.com/posts/article/how-composability-unlocks-crypto-and-everything-else/) by Linda Xie (June 2021) --- [Composability is to software as compounding interest is to finance] (https://a16zcrypto.com/posts/article/composability-is-to-software-as-compounding-interest-is-to-finance/) by Chris Dixon (October 2021) --- [resources & research on DAOs] (https://a16zcrypto.com/posts/tags/daos/) , a16z crypto   Stay Updated:  Let us know what you think: [https://ratethispodcast.com/a16z] (https://ratethispodcast.com/a16z) Find a16z on Twitter: [https://twitter.com/a16z] (https://twitter.com/a16z) Find a16z on LinkedIn: [https://www.linkedin.com/company/a16z] (https://www.linkedin.com/company/a16z) Subscribe on your favorite podcast app: [https://a16z.simplecast.com/] (https://a16z.simplecast.com/) Follow our host: [https://twitter.com/stephsmithio] (https://twitter.com/stephsmithio) Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. ... Read more

02 Dec 2024

1 HR 49 MINS

1:49:49

02 Dec 2024


#823

Death of a Salesforce: Why AI Will Transform Sales

Sales is evolving. AI-native systems are replacing traditional CRM tools, capturing unstructured insights from emails, Slack, surveys, and more in real time. These systems automate early-stage tasks like prospecting and qualification, enabling sales teams to focus on high-value work—while AI provides live coaching and drives decisions across sales, marketing, and product teams. In this episode, a16z partners Joe Schmidt and Marc Andrusko explore the evolution of sales tools and strategies, sharing their insights on what’s driving this shift. Is this the “Death of a Salesforce”? Perhaps that’s an overstatement. But one thing is clear: the future belongs to those who leverage data and AI to drive decisions—not just activities.   Resources: Find Marc Andrusko on X: [https://x.com/mandrusko1] (https://x.com/mandrusko1) Find Joe Schmidt on X: [https://x.com/joeschmidtiv] (https://x.com/joeschmidtiv) Read the original article: [https://a16z.com/ai-transforms-sales/] (https://a16z.com/ai-transforms-sales/)   Stay Updated:  Let us know what you think: [https://ratethispodcast.com/a16z] (https://ratethispodcast.com/a16z) Find a16z on Twitter: [https://twitter.com/a16z] (https://twitter.com/a16z) Find a16z on LinkedIn: [https://www.linkedin.com/company/a16z] (https://www.linkedin.com/company/a16z) Subscribe on your favorite podcast app: [https://a16z.simplecast.com/] (https://a16z.simplecast.com/) Follow our host: [https://twitter.com/stephsmithio] (https://twitter.com/stephsmithio) Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. ... Read more

25 Nov 2024

16 MINS

16:34

25 Nov 2024


#822

The Longevity Imperative: Redefining the Way We Age

What if the biggest challenge of our time isn’t living longer, but living better?  In this episode, we’re tackling one of humanity’s greatest accomplishments—and perhaps its most overlooked challenge: longevity. As more people live past 100, our systems—healthcare, finance, career planning, and even our cultural perceptions of aging—need a fundamental overhaul.  We’re joined by Dr. Andrew Scott, author of The Longevity Imperative, and Vijay Pande a16z’s Bio & Health general partner, to explore how a shift from “sick care” to “health care” could transform our lives. Together, we discuss the implications of longer lifespans, from the individual choices that can improve our healthspans to the economic and societal shifts required to sustain a healthier, more productive aging society.  Join us as we reimagine the future of aging, where living to 100 can be more than survival—it can be a life well-lived.   Resources:  Find Andrew on X: [https://x.com/profandrewscott?lang=en] (https://x.com/profandrewscott?lang=en) Find Vijay on X: [https://x.com/vijaypande] (https://x.com/vijaypande) Learn more about The Longevity Imperative: [https://profandrewjscott.com/the-longevity-imperative/] (https://profandrewjscott.com/the-longevity-imperative/)   Stay Updated:  Let us know what you think: [https://ratethispodcast.com/a16z] (https://ratethispodcast.com/a16z) Find a16z on Twitter: [https://twitter.com/a16z] (https://twitter.com/a16z) Find a16z on LinkedIn: [https://www.linkedin.com/company/a16z] (https://www.linkedin.com/company/a16z) Subscribe on your favorite podcast app: [https://a16z.simplecast.com/] (https://a16z.simplecast.com/) Follow our host: [https://twitter.com/stephsmithio] (https://twitter.com/stephsmithio) Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. ... Read more

18 Nov 2024

40 MINS

40:30

18 Nov 2024


#821

Rebuilding America's Industrial Backbone

America is a country of immense wealth, but our manufacturing infrastructure is struggling to keep pace. In this episode, we discuss the overlooked crisis of American manufacturing and what it means for our national resilience. a16z’s Oliver Hsu hosts a conversation with founders Jordan Black (Senra Systems), Chris Power (Hadrian), and Bryon Hargis (Castelion) on why we need to revive our industrial base — and fast. From outdated regulations to the adoption of automation, they break down the “death by a thousand paper cuts” that has left our production capabilities lagging behind. Yet, it’s not all grim: these founders share how their companies are taking bold, vertically integrated approaches to reinvent the sector and reclaim America's industrial edge.   Resources: Find Chris on X: [https://x.com/2112Power] (https://x.com/2112Power) Find Jordan on X: [https://x.com/jordan__black] (https://x.com/jordan__black) Find Bryon on X: [https://x.com/hargsb] (https://x.com/hargsb) Find Oliver on X: [https://x.com/oyhsu] (https://x.com/oyhsu)   Stay Updated:  Let us know what you think: [https://ratethispodcast.com/a16z] (https://ratethispodcast.com/a16z) Find a16z on Twitter: [https://twitter.com/a16z] (https://twitter.com/a16z) Find a16z on LinkedIn: [https://www.linkedin.com/company/a16z] (https://www.linkedin.com/company/a16z) Subscribe on your favorite podcast app: [https://a16z.simplecast.com/] (https://a16z.simplecast.com/) Follow our host: [https://twitter.com/stephsmithio] (https://twitter.com/stephsmithio) Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. ... Read more

11 Nov 2024

32 MINS

32:34

11 Nov 2024