#33The 7 Most Powerful Moats For AI StartupsIn the early days, the only moat that startups have is speed. Once you make something peop... more03 Oct 202545 MINS45:0503 Oct 2025
#32The FDE Playbook for AI Startups with Bob McGrewBob McGrew helped build some of the most influential technologies of the past two decades.... more12 Sep 202550 MINS50:4212 Sep 2025
#31Anthropic Co-founder: Building Claude Code, Lessons From GPT-3 & LLM System DesignTom Brown co-founded Anthropic after helping build GPT-3 at OpenAI. A self-taught engineer... more21 Aug 202535 MINS35:5621 Aug 2025
#30How to Spend Your 20s in the AI EraAI has upended the once "safe" CS career path. New grads are facing unemployment rates twi... more08 Jul 202538 MINS38:5508 Jul 2025
#29Alexandr Wang: Building Scale AI, Transforming Work with Agents & Competing With ChinaAlexandr Wang started Scale AI to help machine learning teams label data faster.It started... more18 Jun 20251 HR 01 MINS1:01:1218 Jun 2025
#28State-Of-The-Art Prompting For AI AgentsAt first, prompting seemed to be a temporary workaround for getting the most out of large ... more30 May 202531 MINS31:2630 May 2025
#27Startups Ideas You Can Now Build With AIThere's never been a better time to start an AI company. Not just because there are new id... more16 May 202540 MINS40:4616 May 2025
#26Windsurf CEO: Betting On AI Agents, Pivoting In 48 Hours, And The Future of CodingVarun Mohan didn't set out to build one of the fastest-growing AI developer tools. He ... more02 May 202552 MINS52:3502 May 2025
#25How To Navigate Co-Founder DisputesTechnical skills build startups—but oftentimes, people skills can save them. So how do you... more21 Mar 202542 MINS42:0021 Mar 2025
#24Vibe Coding Is The FutureAndrej Karpathy recently coined the term “vibe coding” to describe how LLMs are getting so... more05 Mar 202531 MINS31:3305 Mar 2025
#23How AI Is Changing EnterpriseThe Lightcone hosts sit down with Aaron Levie, the co-founder & CEO of Box, to hear report... more19 Feb 202549 MINS49:2819 Feb 2025
#22How To Get AI Startup IdeasApply to AI Startup School in SF: https://events.ycombinator.com/ai-sus There’s never been... more07 Feb 202543 MINS43:4807 Feb 2025
#21AI Revolution: Why This Is The Best Time To Start A StartupIn this special episode of Lightcone, we’re joined by YC partner and creator of Gmail, Pau... more24 Jan 202539 MINS39:1424 Jan 2025