In his weekly clinical update, Dr. Griffin highlights measles outbreaks throughout the continental US, reviews recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2 before discussing if vaccination protected children from the development of long COVID or cardiovascular diseases associated with virus infection, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, continues to dispel the myth of viral rebound, when to use steroids and the benefits of convalescent plasma, how COVID-19 effects the autonomic nervous system, and if nirmatrelvir-ritonavir protects against adverse cardiovascular effects following SARS-CoV-2 infection. Subscribe (free): <a title= "http://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?id=300973784" href= "https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065">Apple Podcasts</a>, <a href= "https://www.google.com/podcasts?feed=aHR0cDovL3R3aXYubWljcm9iZXdvcmxkLmxpYnN5bnByby5jb20vdHdpdg%3D%3D">Google Podcasts</a>, <a href= "http://twiv.microbeworld.libsynpro.com/twiv">RSS</a>, <a href="http://eepurl.com/Gcw59">email</a> Become a <a href= "https://www.microbe.tv/contribute">patron</a> of TWiV! Links for this episode <ul> <li><a href= "https://www.cdc.gov/measles/cases-outbreaks.html">Measles everywhere</a> (CDC)</li> <li>Respiratory  <a href= "https://www.cdc.gov/surveillance/nrevss/index.html">disease</a> surveillance (CDC)</li> <li>RSV <a href= "https://www.cdc.gov/surveillance/nrevss/rsv/index.html">surveillance</a>  (CDC)</li> <li>RSV <a href= "https://www.cdc.gov/surveillance/nrevss/rsv/natl-trend.html">national</a> trend (CDC)</li> <li>Estimating <a href= "https://www.cdc.gov/mmwr/volumes/73/wr/mm7309a4.htm?s_cid=mm7309a4_e&ACSTrackingID=USCDC_9%2021-%20DM124001&ACSTrackingLabel=This%20Week%20in%20MMWR%3A%20Vol.%2073%2C%20March%207%20%2C%202024&deliveryName=USCDC_921-DM124001">niresevimab</a> effectiveness for infants (MMWR)</li> <li><a href= "https://www.nbcnews.com/health/health-news/kids-died-flu-2024-healthy-cdc-vaccination-rcna134963"> More than 100 children died</a> of influenza (NBS News)</li> <li>Influenza/flu <a href= "https://www.cdc.gov/flu/weekly/index.htm">surveillance </a> (CDC)</li> <li>Influenza/flu <a href= "https://www.cdc.gov/flu/weekly/usmap.htm">map</a> (CDC)</li> <li>COVID-19  <a href= "https://covid.cdc.gov/covid-data-tracker/#trends_weeklyhospitaladmissions_select_00">hospital</a> admissions (CDC)</li> <li>COVID-19 <a href= "https://www.cdc.gov/nwss/rv/COVID19-nationaltrend.html">national</a> trend (CDC)</li> <li>COVID-19 <a href= "https://biobot.io/data/">wastewater</a> testing (biobot)</li> <li><a href= "https://covid.cdc.gov/covid-data-tracker/#variant-proportions"> Variant</a> tracker (CDC)</li> <li><a href= "https://covid.cdc.gov/covid-data-tracker/#trends_weeklyhospitaladmissions_select_00"> Variant hospital</a> admissions (CDC)</li> <li>Did the <a href= "https://publications.aap.org/pediatrics/article/doi/10.1542/peds.2023-064446/196419/Vaccine-Effectiveness-%20Against-Long-COVID-in?autologincheck=redirected">vaccine protect children</a> against Long COVID (Pediatrics)</li> <li><a href= "https://www.nature.com/articles/s41467-024-46497-0">Did</a> COVID-19 vaccination impact cardiovascular diseases? (Nat Comm)</li> <li><a href= "https://www.cdc.gov/coronavirus/2019-ncov/your-health/quarantine-isolation.html"> CDC Quarantine</a> guidelines (CDC)</li> <li><a href= "https://www.cdc.gov/mmwr/volumes/73/wr/mm7308a5.htm">NIH</a> COVID-19 treatment guidelines (NIH)</li> <li>Molnupiravir <a href= "https://onlinelibrary.wiley.com/doi/10.1002/jmv.28011">safety</a> and efficacy (JMV)</li> <li>Convalescent plasma recommendation for <a href= "file:///Users/Amy/Desktop/">immunocompromised</a> (IDSociety)</li> <li>Updated <a href= "https://www.cdc.gov/ncird/whats-new/updated-respiratory-virus-guidance.html">respiratory infection</a> guidelines (CDC)</li> <li>What do when your <a href= "https://www.cdc.gov/coronavirus/2019-ncov/hcp/guidance-risk-%20assesment-hcp.html">heathcare provider </a>is infected with SARS-CoV-2 (CDC)</li> <li>Managing healthcare staffing <a href= "https://www.cdc.gov/coronavirus/2019-ncov/hcp/mitigating-staff-shortages.html">shortages</a> (CDC)</li> <li>Steroids,<a href= "https://academic.oup.com/ofid/article/10/3/ofad105/7055978">dexamethasone</a> at the right time (OFID)</li> <li><a href= "https://www.hematology.org/education/clinicians/guidelines-and-quality-care/clinical-practice-guidelines/venous-thromboembolism-guidelines/ash-guidelines-on-use-of-anticoagulation-in-patients-with-covid-19"> Anticoagulation</a> guidelines (hematology.org)</li> <li>Long COVID trial for <a href= "https://www.nih.gov/news-events/news-releases/nih-opens-long-covid-trials-evaluate-treatments-autonomic-%20nervous-system-dysfunction">autonomic nervous system</a> dysfunction (NIH)</li> <li><a href= "https://link.springer.com/article/10.1007/s10557-024-07570-4"> Nirmatrelvir-ritonavir </a>impact on myocardial injury and long-term cardiovascular outcomes in COVID-19 hospitalized patients (Cardiovascular Drugs and Therapy)</li> <li>Contribute to our <a href= "https://parasiteswithoutborders.com/">ASTMH fundraiser at PWB</a></li> <li><a title="" href= "https://www.microbe.tv/twiv/twiv-1088-letters/">Letter</a><a title="" href= "https://www.microbe.tv/twiv/twiv-1092-letters/">s</a><a title="" href= "https://www.microbe.tv/twiv/twiv-1096-letters/"> read</a> on TWiV 1096</li> <li>Dr. Griffin’s COVID treatment summary (<a title="" href= "https://twiv.s3.amazonaws.com/COVID+treatment+summary+12-21-2023.pdf">pdf</a>)</li> <li>Timestamps by <a href= "https://ramseylab.vercel.app/">Jolene</a>. Thanks!</li> </ul> Intro music is by <a href= "http://www.ronaldjenkees.com/">Ronald Jenkees</a> Send your questions for Dr. Griffin to daniel@microbe.tv

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TWiV 1096: Clinical update with Dr. Daniel Griffin

This Week in Virology