<h3><h2>Support the show</h2>Review the show where ever your listening<a href="https://thepoisonlab.com/support" rel="noopener noreferrer" target="_blank">Join as a supporting member</a><ul><li>Ad free episodes</li><li>Bonus content and early access</li><li>Discounts and give aways on GOTA PICCEM Mushroom card game</li></ul> <a href="https://thepoisonlab.aweb.page/p/cf635c33-5117-4652-abd6-6bedce51444a" rel="noopener noreferrer" target="_blank">The GOTTA PICCEM Poisonous Mushroom Game Landing Page!</a><a href="https://www.etsy.com/shop/ThePoisonLab" rel="noopener noreferrer" target="_blank">Tox trinkets (Rep the show at home!)</a><h2>Reach the show</h2><ul><li>Email: Toxtalk1@gmail.com</li></ul> More Show Resources<ul><li><a href="https://thepoisonlab.aweb.page/p/cf635c33-5117-4652-abd6-6bedce51444a" rel="noopener noreferrer" target="_blank">Get Messages from Toxo (Newsletter)</a></li><li><a href="https://the-poison-lab.yolasite.com/" rel="noopener noreferrer" target="_blank">Ryan's Medical Games and Resources</a></li><li><a href="https://www.thepoisonlab.com" rel="noopener noreferrer" target="_blank">Show Website</a></li></ul> </h3><h3>The Poison Lab: Outbreak – Markham Aconite Poisoning</h3>On August 29, 2022, twelve diners at a Markham, Ontario restaurant fell critically ill with vomiting, numbness, and life-threatening arrhythmias. The culprit? A deadly plant toxin: aconite.In this episode—the first of a new Poison Lab Outbreak series—we go inside the Markham mass poisoning case. Join host Ryan Feldman, clinical toxicologist and emergency medicine pharmacist, as he investigates how a rare and lethal toxin ended up in a restaurant spice jar and nearly cost lives.You’ll hear firsthand from the experts who responded to the outbreak:<ul><li>Dr. Jessica Kent, toxicology fellow at the time at the University of Toronto</li><li>Dr. Abinhay Sathya, intensivist at Markham Stouffville Hospital</li><li>Dr. Margaret Thompson, toxicologist and on-call consultant for the Ontario Poison Centre</li><li>Dr. Randy Purves, research scientist at the Canadian Food Inspection Agency (CFIA)</li><li>Bryn Shurmer, MS- analytical chemist at the Canadian Food Inspection Agency (CFIA)&nbsp;</li></ul> Together, they walk us through the outbreak timeline—from the first patients in VT to the public health investigation that uncovered a mislabeled spice bag full of pure aconite root.Looking for timestamps?A fully timestamped version of the episode—so you can jump to any topic—is available to our <a href="https://www.ThePoisonLab.Com/Support" rel="noopener noreferrer" target="_blank">supporting members</a>.💡 Key topics:<ul><li>Clinical presentation and toxic effects of aconite</li><li>Challenges in mass poisoning recognition and coordination</li><li>The crucial role of poison centers in outbreak response</li><li>Public health trace-back to contaminated galangal powder</li><li>Lessons for emergency departments and toxicologists</li></ul> 📍 Resources & Mentions:<ul><li><a href="https://pubmed.ncbi.nlm.nih.gov/40637172/" rel="noopener noreferrer" target="_blank">Case series about the incident written by Dr. Kent, Sathya, and Thompson</a></li><li><a href="https://x.com/DavidJuurlink/status/1564298196800651265" rel="noopener noreferrer" target="_blank">Twitter/X</a> post by Dr. David Juurlink that helped disseminate early info</li><li><a href="https://thepoisonlab.com/episode/open-and-shut-mystery-case-31-with-guests-dr-dan-mccabe-and-dr-crissy-lawson" rel="noopener noreferrer" target="_blank">The Poison Lab previous aconite episode: Open and shut (Mystery Case #31)</a></li><li><a href="https://pubmed.ncbi.nlm.nih.gov/38613376/" rel="noopener noreferrer" target="_blank">Paper written by Ryan, Dan McCabe, and Crissy Lawson</a></li></ul> 🎧 Listen now at: <a href="http://www.thepoisonlab.com/" rel="noopener noreferrer" target="_blank">www.ThePoisonLab.com</a>💬 Have thoughts or questions? Connect on Instagram @tox_talk, Twitter @LabPoison, or email toxtalk1@gmail.com.

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