<div>Dr. Roger Seheult</div> <div>Dr. Roger Seheult is the co-creator of MedCram Videos. In the early days of the COVID-19 pandemic, MedCram emerged as a beacon of insight, providing continuing coverage and perspectives in an environment almost defined by information scarcity.</div> <div> </div> <div>What particularly excited me about the unique opportunity of this interview is that apart from Dr. Seheult being a unique voice of public scholarship during the early days of the pandemic, he's also a quadruple board-certified pulmonologist with deep experience working on the frontline of the COVID-19 pandemic.</div> In this episode, you'll discover: <ul> <li>00:06:20 How <a href= "https://www.youtube.com/channel/UCG-iSMVtWbbwDDXgXXypARQ?sub_confirmation=1"> MedCram Videos</a> got started and the future of medical education from Dr. Seheult's standpoint.</li> <li>00:09:37 What to do when life is on the line and the usual hierarchy of evidence doesn't exist, as in early emergency COVID-19 treatment.</li> <li>00:12:46 The crucial differences in treating early vs. late-stage COVID-19 illness.</li> <li>00:14:40 How doctors would've treated COVID-19 one-hundred years ago.</li> <li>00:18:13 How increasing ventilation may powerfully impact COVID-19 disease transmission and why airplanes have surprisingly little disease transmission.</li> <li>00:20:28 How masks are virtually universally beneficial in the pandemic regardless of type.</li> <li>00:21:32 Vitamin D and COVID-19</li> <li>00:22:22 How the steroid chemical structure of vitamin D confers qualities on vitamin D that other vitamins ("vital amines") do not possess, such as membrane permeability that provides access to the nucleus and broad gene regulatory effects mediated by a specialized vitamin D receptor element.</li> <li>00:23:24 How calcium homeostasis, which was the early and exclusive focus for scientists and doctors that were trying to determine the ideal vitamin D levels, may have caused the RDA to be set too low since we now know vitamin D regulates around 5% of the protein-encoding genome and have much broader effects.</li> <li>00:24:23 How the hormonal role of vitamin D confers on it properties more similar to other hormones like testosterone and cortisol rather than those of ordinary vitamins.</li> <li>00:26:21 The surprising level of overlap between COVID-19 positivity and groups most affected by vitamin D deficiency and the surprise finding of how less than 50 ng/mL blood levels of vitamin D associated with greater likelihood of SARS-CoV-2 positivity in the hospital.</li> <li>00:30:27 How scientists are able to interrogate the effects of low vitamin D levels through genetic research, a type of study known as mendellian randomization.</li> <li>00:34:20 The gene regulatory effects of vitamin D and the implications for the scale of its biological impact.</li> <li>00:35:49 How Vitamin D's ACE2/renin-angiontensin-promoting effects may be mechanistically involved in the effects observed in vitamin D COVID-19 studies.</li> <li>00:42:00 Why ameliorating vitamin D deficiency in one large monthly bolus might be less effective than daily or weekly doses.</li> <li>00:43:23 How a prescription-only form of vitamin D known as Calcifediol might have an advantage in acute care for COVID-19.</li> <li>00:47:06 Why skin synthesis of vitamin D from UV B radiation can be extraordinarily unreliable when compared to supplementation.</li> <li>00:53:43 What the safest dose range for vitamin D is that should also address deficiency in most populations.</li> <li>01:06:15 The beneficial circadian effect of early morning sunlight.</li> <li>01:07:38 How sleep deprivation is meaningfully implicated in profound and immediate impairment of viral immunity.</li> <li>01:12:08 Dr. Seheult's suggestions for how to achieve the highest quality of sleep.</li> <li>01:19:18 How a century old sanitarium technique used during the Spanish flu era massively boosts interferon by up to ten-times using heat exposure.</li> <li>01:22:38 How genetic and antibody-induced failures of the interferon system underpin up to 14% of all severe cases of COVID-19 and why interferon is so vitally important for viral response.</li> <li>01:26:43 Why treating the symptoms of fever during the spanish flu turned out to not be a good idea, immunologically speaking.</li> <li>01:31:58 Dr. Seheult's on-going research into using hot hydrotherapy as a viral immunity booster.</li> <li>01:47:00 COVID-19 Vaccines</li> </ul>   If you’re interested in learning more, you can read the full show notes here: <a href= "https://www.foundmyfitness.com/episodes/roger-seheult">https://www.foundmyfitness.com/episodes/roger-seheult</a> Join over 300,000 people and get the latest distilled information straight to your inbox weekly: <a href= "https://www.foundmyfitness.com/newsletter">https://www.foundmyfitness.com/newsletter</a> Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: <a href= "https://www.foundmyfitness.com/crowdsponsor">https://www.foundmyfitness.com/crowdsponsor</a>

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#063 Dr. Roger Seheult from MedCram on COVID-19 Vaccines, Vitamin D, and Heat Hydrotherapy

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