In this episode we discuss:
 
<ul>
<li>
Why glucose and fructose are not the primary drivers of AGE formation 
</li>
<li>
Whether blood sugar spikes cause glycation 
</li>
<li>
How fats and ketones can cause glycation 
</li>
<li>
What’s really responsible for glycation in type 2 diabetes 
</li>
<li>
Whether fructose causes more glycation than glucose
</li>
</ul>
 
Check out the Energy Balance Solution program here: <a href='https://www.jayfeldmanwellness.com/solution/'>https://www.jayfeldmanwellness.com/solution/</a> 
 
Click here to check out the show notes: 
<a href='https://www.jayfeldmanwellness.com/eb-136-eric-westman-debate-follow-up-part-2-high-carb-diets-cause-insulin-resistance-overeating-and-glycation/'>httpshttps://www.jayfeldmanwellness.com/eb-137-what-really-causes-glycation-is-sugar-really-the-problem/</a> 

 

Timestamps:
0:00 – intro 
0:46 – common beliefs about carbohydrates and glycation 
2:35 – what are glycation and advanced glycation end products? 
6:57 – the process of glycation from glucose 
9:30 – is sugar the only source of AGEs? 
15:00 – primary drivers of glycation: dicarbonyls 
19:30 – how fatty acids, amino acids, and ketones cause AGE formation 
21:23 – how increased gluconeogenesis on low-carb diets increases AGE formation 
22:53 – glucose metabolism produces very few glycation products in the context of a healthy metabolism 
25:33 – omega-6s form AGEs more than 10x faster than glucose 
28:24 – the role of ALEs (advanced lipoxidation end products) in glycation and chronic disease 
30:36 – whether blood sugar spikes cause glycation 
38:52 – whether fructose causes more glycation (or fructation) than glucose 
47:05 – can glycation from fructose (fructation) be measured, and does this matter? 
52:06 – problems with research looking at fructose’s AGE formation in animal models

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EB. 137: What REALLY Causes Glycation (Is Sugar Really the Problem?)

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