How do our biological systems work together to respond to chronic stress? What do these responses mean for early learning and lifelong health? And when we say that early experiences matter, what do we mean by early? This episode of The Brain Architects podcast addresses all these questions and more!


Contents
Podcast
Panelists
Additional Resources
Transcript


To kick off this episode, Center Director Dr. Jack Shonkoff describes the body&#039;s stress response system, how our biological systems act as a team when responding to chronic stress, and the effects chronic stress can have on lifelong health.

This is followed by a discussion among a panel of scientists including Dr. Nicki Bush (University of California-San Francisco),  Dr. Damien Fair (University of Minnesota),  and Dr. Fernando Martinez (University of Arizona). The panelists discuss how our bodies respond to adversity, inflammation&#039;s role in the stress response system, the effects of stress during the prenatal period and first few years after birth, and how we can use this science to prevent long-term impacts on our health.


Panelists


Dr. Nicki Bush

Dr. Damien Fair

Dr. Fernando Martinez


Additional Resources
Resources from the Center on the Developing Child

 	

 	Working Paper 15: Connecting the Brain to the Rest of the Body: Early Childhood Development and Lifelong Health Are Deeply Intertwined
 	InBrief: Connecting the Brain to the Rest of the Body
 	Health and Learning Are Deeply Interconnected in the Body: An Action Guide for Policymakers
 	What Is Inflammation? And Why Does it Matter for Child Development?
 	How Racism Can Affect Child Development



Articles

 	Biel, M.G., Tang, M.H., &amp; Zuckerman, B. (2020). Pediatric mental health care must be family mental health care. JAMA Pediatrics, 174(6):519-520.
 	Bush, N.R., Savitz, J., Coccia, M., et al. (2020). Maternal stress during pregnancy predicts infant infectious and noninfectious illness. The Journal of Pediatrics.
 	Graignic-Philippe, R., Dayan, J., Chokron, S., et al. (2014). Effects of prenatal stress on fetal and child development: A critical literature review. Neuroscience &amp; Biobehavioral Reviews, 43, 137-162.
 	LeWinn, K.Z., Bush, N.R., Batra, A.B., et al. (2020). Identification of modifiable social and behavioral factors associated with child cognitive performance. JAMA Pediatrics, 174(11):1063-1072.
 	O’Connor, T.G., Monk, C., &amp; Fitelson, E.M. (2014). Practitioner review: Maternal mood in pregnancy and child development: Implications for child psychology and psychiatry. J Child Psychol Psychiatry, 55(2): 99-111.
 	Racine, N., Plamondon, A., Madigan, S., et al. (2018). Maternal adverse childhood experiences and infant development. Pediatrics, 141(4).
 	Shonkoff, J.P., Boyce, W.T., Levitt, P., et all (in press). It’s about more than just the brain: The biology of early adversity and resilience and the future of primary care pediatrics.


Transcript
Sally: Welcome to The Brain Architects, a podcast from the Center on the Developing Child at Harvard University. I&#039;m your host Sally Pfitzer. Our center believes that advances in science can provide a powerful source of new ideas that can improve outcomes for children and families. We want to help you apply the science of early childhood development to your everyday interactions with children and take what you&#039;re hearing from our experts and panels and apply it to your everyday work.

 In today&#039;s episode, we&#039;ll discuss how early experiences, especially during the prenatal period and first few years after a baby is born, get inside the body and can have long-term impacts on lifelong health. Here to help us dig into that science around the early years and lifelong health is Dr. Jack Shonkoff who is the Professor of Child Health and Development, and the Director of the Center on the Developing Child at Harvard University. Hi Jack. It&#039;s really great to have you back. 

Jack: Hi Sally.

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Connecting Health and Learning Part I: The Science

Center on the Developing Child at Harvard University