<p>ALS is a fatal neurological disease that kills motor neurons. Even though it was first described more than 150 years ago, there is no cure, and the few drugs available only dampen the symptoms or slow the progression by a few months. In recent years new drugs have emerged. However, there is one problem: the life expectancy is just two to five years after diagnosis. This timeline is incompatible with the FDA drug approval process, which takes years and even decades. This has created a tense situation for desperate patients who are demanding the FDA approve unproven drugs. What’s the harm in giving desperate patients an imperfect drug?</p> Credits <p>Host: <a href= "https://www.sciencehistory.org/profile/alexis-j-pedrick">Alexis Pedrick</a> Senior Producer: <a href= "https://www.sciencehistory.org/profile/mariel-carr">Mariel Carr</a> Producer: <a href= "https://www.sciencehistory.org/profile/rigoberto-hernandez">Rigoberto Hernandez</a> Associate Producer: <a href= "https://www.sciencehistory.org/profile/sarah-kaplan/">Sarah Kaplan</a> Audio Engineer: <a href="https://www.podbrain.org/" target= "_blank" rel="noreferrer noopener">Jonathan Pfeffer</a> “Color Theme” composed by <a href= "https://www.podbrain.org/" target="_blank" rel= "noreferrer noopener">Jonathan Pfeffer</a>. Additional music by <a href="https://www.sessions.blue/" target= "_blank" rel="noreferrer noopener">Blue Dot Sessions</a></p>

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ALS Patients Take on the FDA

Distillations | Science History Institute

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