In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses the link between in utero SARS-CoV-2 infection and poor neurodevelopment outcomes, the use of an mRNA vaccine as an anti-cancer therapy, why one should receive the HPV vaccine, asymptomatic H5N1 isolations in humans, and H5N1 on turkey farms, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how two vaccinated physicians became infected with measles, effective of COVID-19 vaccine for children, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, how a specific antibody type may associate with recovery from long COVID, if use of a probiotic is helpful to treat mild COVID-19, if vaccination helps prevent long in adolescents and contacting your federal government representative to stop the assault on science and biomedical research. <div class="fluid-width-video-wrapper">Subscribe (free): <a title= "http://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?id=300973784" href= "https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065"> Apple Podcasts</a>, <a href= "https://backfeed.strangecode.com/GZA5raQg2EIeWv8A5Z/http://twiv.microbeworld.libsynpro.com/twiv">RSS</a>, <a href="http://eepurl.com/Gcw59">email</a></div> Become a <a href= "https://www.microbe.tv/contribute">patron</a> of TWiV! <h3 id="links-for-this-episode" class="wp-block-heading"> Links for this episode</h3> <ul class="wp-block-list"> <li><a href= "https://journals.lww.com/greenjournal/abstract/9900/neurodevelopmental_outcomes_of_3_year_old_children.1392.aspx"> Neurodevelopmental Outcomes</a> of 3-Year-Old Children Exposed to Maternal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Utero (Obstetrics & Gynecology)</li> <li>SARS-CoV-2 mRNA vaccines <a href= "https://www.nature.com/articles/s41586-025-09655-y">sensitize tumours</a> to immune checkpoint blockade (Nature)</li> <li>TWiV 1267: A <a href= "https://www.youtube.com/watch?v=jCpHyAPpww8&t=1060s">cancer vaccine</a> and an mpox treatment (microbeTV: TWiV1267)</li> <li>Cancers Caused by <a href= "https://www.cdc.gov/hpv/about/cancers-caused-by-hpv.html">HPV</a> (CDC: Human papillomavirus (HPV))</li> <li>Circulating <a href= "https://academic.oup.com/jnci/advance-article-abstract/doi/10.1093/jnci/djaf249/8248381?redirectedFrom=fulltext&login=false#google_vignette">tumor human papillomavirus</a> DNA whole genome sequencing enables human papillomavirus-associated oropharynx cancer early detection (Journal of National Cancer Institute)</li> <li>Impact of <a href= "https://www.mdpi.com/1999-4915/17/10/1377">Vaccinating</a> Adult Women Who Are HPV-Positive or with Confirmed Cervical SIL with the 9-Valent Vaccine (Viruses)</li> <li>ACIP Shared Clinical <a href= "https://www.cdc.gov/acip/vaccine-recommendations/shared-clinical-decision-making.html?CDC_AAref_Val=https://www.cdc.gov/vaccines/acip/acip-scdm-faqs.html">Decision-Making</a> Recommendations (CDC: Advisory Committee on Immunization Practices (ACIP))</li> <li><a href= "https://www.cdc.gov/vaccines/vpd/hpv/hcp/recommendations.html#:~:text=HPV%20Vaccine%20%5B1page%5D-,Dosing%20Schedules,of%20the%20acute%20illness%20improve"> HPV</a> Vaccination Recommendation (CDC: Vaccines & Immunizations)</li> <li><a href= "https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2840680"> Asymptomatic</a> Human Infections With Avian Influenza A(H5N1) Virus Confirmed by Molecular and Serologic Testing (JAMA: OPEN Network)</li> <li>Review: Human <a href= "https://www.cidrap.umn.edu/avian-influenza-bird-flu/review-human-h5n1-avian-flu-cases-can-be-asymptomatic-and-virus-likely">H5N1</a> avian flu cases can be asymptomatic, and the virus likely spreads among people (CIDRAP)</li> <li>Avian flu strikes <a href= "https://www.cidrap.umn.edu/avian-influenza-bird-flu/avian-flu-strikes-turkey-farms-dakotas-large-egg-facility-california">turkey</a> farms in Dakotas, large egg facility in California (CIDRAP)</li> <li><a href= "https://www.gov.il/en/pages/01112025-01">Another Doctor</a> at Ichilov Contracts Measles After Treating Unvaccinated Child (gov.il)</li> <li><a href= "https://data.wastewaterscan.org/tracker/?charts=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%3D&selectedChartId=668c22"> Wastewater</a> for measles (WasterWater Scan)</li> <li>Measles <a href= "https://www.cdc.gov/measles/data-research/index.html">cases and outbreaks</a> (CDC Rubeola)</li> <li>Tracking <a href= "https://publichealth.jhu.edu/ivac/resources/us-measles-tracker">Measles Cases</a> in the U.S. (Johns Hopkins)</li> <li>Measles vaccine recommendations from NYP (<a href= "https://b2927012.smushcdn.com/2927012/wp-content/uploads/sites/2/measles_vax_rec_2.png?lossy=2&strip=1&webp=1">jpg</a>)</li> <li><a href= "https://health-infobase.canada.ca/measles-rubella/">Weekly</a> measles and rubella monitoring (Government of Canada)</li> <li><a href= "https://www.who.int/news-room/fact-sheets/detail/measles">Measles</a> (WHO)</li> <li>Get the <a href= "https://www.health.ny.gov/diseases/communicable/measles/">FACTS</a> about measles (NY State Department of Health)</li> <li><a href= "https://www.cdc.gov/measles/hcp/vaccine-considerations/index.html"> Measles</a> (CDC Measles (Rubeola))</li> <li><a href= "https://www.cdc.gov/measles/index.html">Measles</a> vaccine (CDC Measles (Rubeola))</li> <li><a href= "file:///Users/Amy/Desktop/Measles%20(CDC%20Measles%20(Rubeola))"> Presumptive evidence</a> of measles immunity (CDC)</li> <li><a href= "https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-13-measles.html#cdc_report_pub_study_section_9-contraindications-and-precautions-to-vaccination"> Contraindications and precautions</a> to measles vaccination (CDC)</li> <li><a href= "https://www.cdc.gov/measles/hcp/vaccine-considerations/index.html"> Measles</a> (CDC Measles (Rubeola))</li> <li>Adverse events associated with <a href= "https://www.ncbi.nlm.nih.gov/books/NBK236284/#:~:text=The%20evidence%20favors%20acceptance%20of,in%20temporal%20relation%20to%20vaccination">childhood vaccines</a>: evidence bearing on causality (NLM)</li> <li>Measles <a href= "https://www.idsociety.org/public-health/measles/know-the-facts/">Vaccination:</a> Know the Facts (ISDA: Infectious Diseases Society of America)</li> <li>Deaths following vaccination: what does the <a href= "https://www.sciencedirect.com/science/article/abs/pii/S0264410X15006556?via%3Dihub">evidence show</a> (Vaccine)</li> <li>Influenza: Waste water scan for <a href= "https://data.wastewaterscan.org/?charts=CjIQACABSABaBk4gR2VuZXIKMjAyNC0wOC0wN3IKMjAyNC0wOS0xOIoBBmQ0MzllMsABAQ%3D%3D&selectedChartId=d439e2">11 pathogens</a> (WastewaterSCan)</li> <li>US<a href= "https://www.cdc.gov/respiratory-viruses/data/activity-levels.html"> respiratory</a> virus activity (CDC Respiratory Illnesses)</li> <li>Respiratory virus <a href= "https://www.cdc.gov/respiratory-viruses/data/activity-levels.html">activity</a> levels (CDC Respiratory Illnesses)</li> <li>Weekly surveillance report: <a href= "https://www.cdc.gov/fluview/surveillance/2024-week-37.html">clift notes</a> (CDC FluView)</li> <li><a href= "https://www.cdc.gov/flu/hcp/acip/index.html">ACIP</a> Recommendations Summary (CDC: Influenza)</li> <li>Influenza Vaccine Composition for the <a href= "https://www.fda.gov/vaccines-blood-biologics/influenza-vaccine-composition-2025-2026-us-influenza-season?mtm_source=25">2025-2026</a> U.S. Influenza Season (FDA)</li> <li>RSV: Waste water scan for <a href= "https://data.wastewaterscan.org/?charts=CjIQACABSABaBk4gR2VuZXIKMjAyNC0wOC0wN3IKMjAyNC0wOS0xOIoBBmQ0MzllMsABAQ%3D%3D&selectedChartId=d439e2">11 pathogens</a> (WastewaterSCan)</li> <li><a href= "https://www.pophive.org/respiratory-diseases/respiratory-syncytial-virus"> Respiratory Diseases</a> (Yale School of Public Health)</li> <li>US<a href= "https://www.cdc.gov/respiratory-viruses/data/activity-levels.html"> respiratory</a> virus activity (CDC Respiratory Illnesses)</li> <li>RSV-<a href= "https://www.cdc.gov/rsv/php/surveillance/rsv-net.html">Net</a>work (CDC Respiratory Syncytial virus Infection)</li> <li><a href= "https://www.cdc.gov/rsv/vaccines/adults.html">Vaccines for Adults</a> (CDC: Respiratory Syncytial Virus Infection (RSV))</li> <li><a href= "https://www.cdc.gov/acip/downloads/slides-2025-04-15-16/04-Ortega-Sanchez-Adult-RSV-508.pdf"> Economic Analysis</a> of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)</li> <li>Waste water scan for <a href= "https://data.wastewaterscan.org/?charts=CjIQACABSABaBk4gR2VuZXIKMjAyNC0wOC0wN3IKMjAyNC0wOS0xOIoBBmQ0MzllMsABAQ%3D%3D&selectedChartId=d439e2">11 pathogens</a> (WastewaterSCan)</li> <li>COVID-19 <a href= "https://covid.cdc.gov/covid-data-tracker/#maps_percent-covid-deaths">deaths</a> (CDC)</li> <li>Respiratory Illnesses <a href= "https://www.cdc.gov/respiratory-viruses/data/index.html">Data Channel</a> (CDC: Respiratory Illnesses)</li> <li>COVID-19 <a href= "https://www.cdc.gov/nwss/rv/COVID19-nationaltrend.html">national and regional</a> trends (CDC)</li> <li>COVID-19 <a href= "https://covid.cdc.gov/covid-data-tracker/index.html#variant-proportions">variant tracker</a> (CDC)</li> <li>SARS-CoV-2 <a href= "https://nextstrain.org/ncov/gisaid/global/all-time?d=tree,frequencies&p=full&r=division&showBranchLabels=all&tl=none">genomes</a> galore (Nextstrain)</li> <li>Antigenic and Virological Characteristics of SARS-CoV-2 Variant <a href= "https://www.biorxiv.org/content/10.1101/2025.04.30.651462v1.full.pdf">BA.3.2, XFG, and NB.1.8.1</a> (bioRxiV)</li> <li>Vascular and inflammatory diseases after COVID-19 infection and vaccination in <a href= "https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642%2825%2900247-0/fulltext">children and young people</a> in England (LANCET: Child & Adolescent Health)</li> <li><a href= "https://www.pemgarda.com/hcp/infusion-center-locator/">Where</a> to get pemgarda (Pemgarda)</li> <li><a href= "https://investors.adagiotx.com/news-releases/news-release-details/invivyd-announces-fda-authorization-emergency-use-pemgardatm"> EUA</a> for the pre-exposure prophylaxis of COVID-19 (INVIYD)</li> <li>Infusion <a href= "https://primeinfusions.com/locations/">center</a> (Prime Fusions)</li> <li><a href= "https://www.cdc.gov/respiratory-viruses/guidance/faqs.html?CDC_AAref_Val=https://www.cdc.gov/respiratory-viruses/guidance/faq.html"> CDC Quarantine</a> guidelines (CDC)</li> <li><a href= "https://www.ncbi.nlm.nih.gov/books/NBK570371/">NIH</a> COVID-19 treatment guidelines (NIH)</li> <li>Drug interaction <a href= "https://covid19-druginteractions.org/checker">checker</a> (University of Liverpool)</li> <li>Help your eligible <a href= "https://paxlovid.pfizerpro.com/access-resources/access">patients access</a> PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)</li> <li>Understanding<a href= "https://paxlovid.iassist.com/"> Coverage</a> Options (PAXCESS)</li> <li>Real-World Effectiveness of Nirmatrelvir-Ritonavir in <a href= "https://academic.oup.com/cid/advance-article-abstract/doi/10.1093/cid/ciaf145/8305867?redirectedFrom=fulltext&utm_source=advanceaccess&utm_campaign=cid&utm_medium=email">Preventing</a> Coronavirus Disease 2019–Associated Hospitalization (CID)</li> <li><a href= "https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/#ExecutiveSummaryandBackground"> Infectious Disease Society guidelines</a> for treatment and management (ID Society)</li> <li>Molnupiravir <a href= "https://onlinelibrary.wiley.com/doi/10.1002/jmv.28011">safety</a> and efficacy (JMV)</li> <li>Convalescent plasma recommendation for <a href= "https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/">immunocompromised</a> (ID Society)</li> <li>What to do when sick with a <a href= "https://www.cdc.gov/ncird/whats-new/updated-respiratory-virus-guidance.html">respiratory virus</a> (CDC)</li> <li>Managing healthcare staffing <a href= "https://www.cdc.gov/covid/hcp/infection-control/mitigating-staff-shortages.html?CDC_AAref_Val=https://www.cdc.gov/coronavirus/2019-ncov/hcp/mitigating-staff-shortages.html">shortages</a> (CDC)</li> <li><a href= "https://www.hematology.org/education/clinicians/guidelines-and-quality-care/clinical-practice-guidelines/venous-thromboembolism-guidelines/ash-guidelines-on-use-of-anticoagulation-in-patients-with-covid-19"> Anticoagulation</a> guidelines (hematology.org)</li> <li>Daniel Griffin's <a href= "https://academic.oup.com/ofid/article/11/9/ofae462/7733485">evidence based</a> medical practices for long COVID (OFID)</li> <li>Long COVID <a href= "https://www.columbiadoctors.org/health-library/article/long-covid/">hotline</a> (Columbia : Columbia University Irving Medical Center)</li> <li><a href="https://longcovidtheanswers.com/">The answers:</a> Long COVID</li> <li>SARS-CoV-2 spike-specific <a href= "https://www.journalofinfection.com/article/S0163-4453%2825%2900241-5/fulltext">IgG4 class switching</a> associates with clinical recovery in Long COVID (Journal of Infection)</li> <li>Efficacy of <a href= "https://link.springer.com/article/10.1007/s40121-025-01246-8">Lactococcus lactis </a>Strain Plasma in Patients with Mild COVID-19 (Infectious Diseases and Therapy)</li> <li>Preventive effect of vaccination on long COVID in <a href= "https://www.sciencedirect.com/science/article/pii/S0264410X25012046">adolescents</a> with SARS-CoV-2 infection (Vaccine)</li> <li>Reaching out to <a href= "https://www.house.gov/representatives/find-your-representative">US house representative</a></li> <li><a title="" href= "https://www.microbe.tv/twiv/twiv-1268-letters/">Letters read</a> on TWiV 1268</li> <li>Dr. Griffin's COVID treatment summary (<a title="" href= "https://twiv.s3.amazonaws.com/COVID+treatment+summary+032224.pdf">pdf</a>)</li> <li>Timestamps by <a href= "https://ramseylab.vercel.app/">Jolene Ramsey</a>. Thanks!</li> </ul> Intro music is by <a href= "http://www.ronaldjenkees.com/">Ronald Jenkees</a> Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

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