A partial government shutdown enters its fourth day as House Republicans weigh whether to back a Senate deal that would reopen most agencies while giving Congress two weeks to negotiate changes to immigration enforcement.The U.S. is set to reopen nuclear talks with Iran, as regional powers push diplomacy even while President Trump warns military action remains on the table.And investigators in Arizona say 84-year-old Nancy Guthrie, the mother of Today show host Savannah Guthrie, may have been abducted from her home as an urgent search continues. Want more analysis of the most important news of the day, plus a little fun? <a href="https://www.npr.org/newsletter/news"target="_blank" >Subscribe</a> to the Up First newsletter.Today’s episode of Up First was edited by Jason Breslow, James Hider, Miguel Macias, Martha Ann Overland, Mohamad ElBardicy, and Alice Woelfle.It was produced by Ziad Buchh, Nia Dumas and Christopher Thomas.We get engineering support from Neisha Heinis. Our technical director is Carleigh Strange.Our Supervising Senior Producer is Vince Pearson.(0:00) Introduction(01:54) Government Shutdown Day 4(05:31) US-Iran Nuclear Talks(09:06) Guthrie Investigation Learn more about sponsor message choices: <a href="https://podcastchoices.com/adchoices">podcastchoices.com/adchoices</a> <a href="https://www.npr.org/about-npr/179878450/privacy-policy">NPR Privacy Policy</a>

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