Vice President JD Vance is heading to Pakistan this weekend to lead peace talks with Iran, as the ceasefire is already under enormous stress. More than 300 people have been killed in Lebanon since Israel's massive offensive Wednesday, with Netanyahu telling Israelis the strikes will not stop even as he says he'll open direct talks with Lebanon for the first time in history. And the Artemis II crew splashes down near California tonight after a record-breaking trip around the moon. Want more analysis of the most important news of the day, plus a little fun? <a href="https://www.npr.org/newsletter/news"target="_blank" >Subscribe</a> to the Up First newsletter. Today’s episode of Up First was edited by Rebekah Metzler, Gerry Holmes, Amina Khan, Mohamad ElBardicy, and Taylor Haney. It was produced by Ziad Buchh and Ava Pukatch. Our director is Kaity Kline. We get engineering support from Neisha Heinis. Our technical director is Carleigh Strange. And our Executive Producer is Jay Shaylor. (0:00) Introduction(01:58) Vance Iran Negotiations(05:30) Israel-Lebanon Talks(09:23) Artemis II Return To Earth To manage podcast ad preferences, review the links below: See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for sponsorship and to manage your podcast sponsorship preferences. <a href="https://www.npr.org/about-npr/179878450/privacy-policy">NPR Privacy Policy</a>

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