TWiM explains how competition for nutrients anticipates and potentially mitigate drug side effects on the gut microbiota, and metabolic control of porin permeability influences antibiotic resistance. Become a <a style="text-decoration: none;" href= "http://www.microbe.tv/contribute"> patron</a> of TWiM. Links for this episode: <ul style= "margin-top: 0px; margin-bottom: 0px; padding-inline-start: 48px;"> <li dir="ltr" style= "list-style-type: disc; font-size: 12pt; font-family: Arial, sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-variant-alternates: normal; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-position: normal; font-variant-emoji: normal; text-decoration: none; vertical-align: baseline; white-space: pre;" aria-level="1"> Nutrient competition predicts <a style= "text-decoration: none;" href= "https://www.cell.com/cell/abstract/S0092-8674(25)01243-7"> drug effects on microbiota</a> (Cell) </li> <li dir="ltr" style= "list-style-type: disc; font-size: 12pt; font-family: Arial, sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-variant-alternates: normal; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-position: normal; font-variant-emoji: normal; text-decoration: none; vertical-align: baseline; white-space: pre;" aria-level="1"> Metabolic control of <a style="text-decoration: none;" href= "https://www.nature.com/articles/s41564-025-02175-5"> porin permeability</a> influences antibiotic resistance in E coli (Nat Micro) </li> <li dir="ltr" style= "list-style-type: disc; font-size: 12pt; font-family: Arial, sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-variant-alternates: normal; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-position: normal; font-variant-emoji: normal; text-decoration: none; vertical-align: baseline; white-space: pre;" aria-level="1"> <a style="text-decoration: none;" href= "https://phisanti.github.io/"> Santiago Cano-Muniz</a> </li> </ul> <p style= "list-style-type: disc;font-size: 12pt;font-family: Arial, sans-serif;color: rgb(0, 0, 0);background-color: transparent;font-weight: 400;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;font-variant-alternates: normal;font-variant-numeric: normal;font-variant-east-asian: normal;font-variant-position: normal;font-variant-emoji: normal;text-decoration-color: currentcolor;text-decoration-line: none;text-decoration-style: solid;text-decoration-thickness: auto;vertical-align: baseline;text-wrap-mode: nowrap;white-space-collapse: preserve;"> Music used on TWiM is composed and performed by <a style= "text-decoration: none;" href= "http://ronaldjenkees.com/"> Ronald Jenkees</a> and used with permission. Send your microbiology questions and comments to twim@microbe.tv

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346: Metabolism and Porin Permeability

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