TWiV explains the 1953 paper by Watson & Crick proposing a structure for DNA, and the role of Epstein-Barr virus in triggering the autoimmune disease systemic lupus erythematosus. Hosts: <a title="" href="https://en.wikipedia.org/wiki/Vincent_Racaniello">Vincent Racaniello</a>, <a title="" href= "https://medschool.umich.edu/profile/879/katherine-spindler">Kathy Spindler</a>, and <a title="" href= "https://bbarkerdrew.com/">Brianne Barker</a> Subscribe (free): <a title= "http://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?id=300973784" href= "https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065"> Apple Podcasts</a>, <a href= "http://twiv.microbeworld.libsynpro.com/twiv">RSS</a>, <a href="http://eepurl.com/Gcw59">email</a> Become a <a href= "https://www.microbe.tv/contribute">patron</a> of TWiV! Links for this episode <ul class="wp-block-list"> <li><a title="" href="https://www.microbe.tv/contribute">Support science education </a>at MicrobeTV</li> <li>Immune 100 <a title="" href= "https://www.eventbrite.com/e/immune-100-live-in-nyc-tickets-1797664816859?aff=oddtdtcreator">live at the Incubator</a></li> <li><a href= "https://www.npr.org/sections/shots-health-news/2025/11/20/nx-s1-5615040/cdc-rfk-childhood-vaccines-autism"> CDC revives debunked ‘link’ between childhood vaccines and autism</a> (npr)</li> <li>A structure for deoxyribose nucleic acid (Nature <a title= "" href= "https://www.mskcc.org/teaser/1953-nature-papers-watson-crick-wilkins-franklin.pdf">pdf</a>)</li> <li><a href= "https://www.atsjournals.org/doi/full/10.1164/rccm.2302011">Three Papers, Three Lessons</a> (Am J Resp Crit Care Med)</li> <li>Discovery of <a title="" href= "https://profiles.nlm.nih.gov/spotlight/sc/feature/doublehelix">Double Helix</a> (Crick Papers)</li> <li>Jim Watson was <a title="" href= "https://www.nytimes.com/2025/11/16/opinion/james-watson-dna.html?unlocked_article_code=1.2k8.VzXR.gxeSwp-B8_Yp&smid=nytcore-ios-share&referringSource=articleShare">blinded by DNA</a> (NY Times)</li> <li>What <a title="" href= "https://www.nature.com/articles/d41586-023-01313-5">Rosalind Franklin contributed</a> (Nature)</li> <li>EBV reprograms <a title="" href= "https://pubmed.ncbi.nlm.nih.gov/41223250/">autoreactive B-cells in lupus</a> (Sci Transl Med)</li> <li>EBV and the <a title="" href= "https://www.science.org/doi/10.1126/scitranslmed.aec0501">making of lupus</a> (Sci Transl Med)</li> <li>Timestamps by <a href= "https://ramseylab.vercel.app/">Jolene</a> Ramsey. Thanks!</li> </ul> Weekly Picks Brianne – <a href= "https://cvr-engagement.co.uk/virus-snowflakes">Virus snowflakes</a> Kathy – <a href= "https://www.youtube.com/watch?v=yvY61ArnxPg&list=PLkCzlk8e8aNfPZoSgvp6m-aRmY4lsUbD6&index=3&pp=iAQB">When “Physic(k)s Lost Its ‘k’ and other Language Quarks</a> Vincent – <a href= "https://en.wikipedia.org/wiki/The_Peripheral">The Peripheral </a>by William Gibson Intro music is by <a href= "http://www.ronaldjenkees.com/">Ronald Jenkees</a> Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

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TWiV 1273: EBV and lupus have not escaped our notice

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