Pancreatic Cancer Halted by Virus Injection&nbsp;Researchers injected an engineered virus directly into pancreatic tumors in three patients — the virus replicated inside malignant cells, triggered an immune response, and stopped tumor growth and spread at an intentionally low early dose. Host Dave Asprey breaks down why oncolytic viruses can do what chemotherapy can't, how the tumor's dense biological wall becomes less of an advantage when a virus can replicate inside it directly, and why a measurable response at a safety dose is the kind of early signal that changes how he's watching this field.&nbsp;Sources:&nbsp;<a href="https://www.newscientist.com/" rel="noopener noreferrer" target="_blank">https://www.newscientist.com</a>&nbsp;&nbsp;AI Chatbots and Teen Mental Health&nbsp;A new survey shows&nbsp;roughly one&nbsp;in five&nbsp;adolescents&nbsp;and young adults are now going to AI chatbots when they feel sad, anxious, nervous, or stressed, with usage heaviest in the 18–21 range. Host Dave Asprey explains why general-purpose language models designed to be engaging are dangerous as a substitute for real mental health support, why false reassurance from a chatbot may make the pipeline to real care harder to reach, and why this is a health systems story masquerading as a tech adoption story — and what parents need to do about it.&nbsp;Sources:&nbsp;<a href="https://www.nbcnews.com/" rel="noopener noreferrer" target="_blank">https://www.nbcnews.com</a>&nbsp;&nbsp;GLP-1 Drugs Cut Breast Cancer Risk&nbsp;Penn Medicine published a retrospective analysis of over&nbsp;111,000 women&nbsp;finding GLP-1 exposure associated with about 35% lower odds of breast cancer in the full cohort and around 30% lower in a matched comparison group. Host Dave Asprey breaks down why this isn't just a weight loss story — it's a metabolic dysfunction story — explains the insulin resistance, inflammation, and hormonal environment mechanisms that may be driving the signal, and makes the case that this finding should be reshaping how oncologists and OBGYNs think about high-risk patients right now.&nbsp;Sources:&nbsp;<a href="https://www.pennmedicine.org/" rel="noopener noreferrer" target="_blank">https://www.pennmedicine.org</a>&nbsp;&nbsp;Putin's $26 Billion Longevity Program&nbsp;The Wall Street Journal reports that Russia has made anti-aging research a Kremlin-level national priority through a&nbsp;$26 billion&nbsp;program including gene therapy, organ bioprinting, and xenotransplantation, led by Putin's daughter Maria Vorontsova and physicist Mikhail Kovalchuk. Host Dave Asprey breaks down what's geopolitical theater, what's legitimately frontier science, and why the real question is whether any findings will make it out to the broader research community or get locked inside a state program.&nbsp;Sources:&nbsp;<a href="https://www.wsj.com/" rel="noopener noreferrer" target="_blank">https://www.wsj.com</a>&nbsp;<a href="https://www.france24.com/" rel="noopener noreferrer" target="_blank">https://www.france24.com</a>&nbsp;&nbsp;Sauna vs. Cold Plunge&nbsp;A landmark Finnish study tracked over 2,300 men for&nbsp;nearly 21&nbsp;years and found increasing sauna frequency associated with dramatically lower cardiovascular and all-cause mortality — strongest at four or more sessions per week. Host Dave Asprey settles the debate with the actual data, explains what heat shock proteins and cold shock proteins actually are and why the evidence base behind them is nowhere near equivalent, and calls out the wellness marketing presenting early-stage mouse model research as the cold water equivalent of two decades of human mortality outcomes.&nbsp;Sources:&nbsp;<a href="https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2521522" rel="noopener noreferrer" target="_blank">https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2521522</a>&nbsp;&nbsp;This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on cancer treatment breakthroughs, adolescent mental health and AI, metabolic drivers of disease, geopolitical longevity science, and the&nbsp;real evidence&nbsp;behind popular recovery modalities. Host Dave Asprey connects emerging clinical research, objective epidemiological data, and real-world optimization protocols into actionable frameworks for extending&nbsp;healthspan, sharpening performance, and staying ahead of the science.&nbsp;&nbsp;New episodes every Tuesday, Thursday, Friday, and Sunday.&nbsp;&nbsp;Keywords: oncolytic virus pancreatic cancer, engineered virus tumor treatment, AI chatbot teen mental health, adolescent AI emotional support, GLP-1 breast cancer risk, semaglutide cancer prevention, metabolic dysfunction root cause disease, Putin longevity program Russia, New Health Preservation Technologies, anti-aging biotech geopolitics, sauna longevity mortality data, cold plunge cold shock proteins, RBM3 heat shock proteins, sauna vs cold plunge evidence, biohacking news 2026, longevity research, Dave Asprey, The Human Upgrade&nbsp;&nbsp;Thank you to our sponsors!&nbsp;&nbsp;-&nbsp;Suppgrade&nbsp;Labs | Grab your DAKE and Minerals 101 duo at&nbsp;<a href="http://shopsuppgradelabs.com/" rel="noopener noreferrer" target="_blank">shopsuppgradelabs.com</a>&nbsp;and use code DAVEPOD for 15% off today&nbsp;-&nbsp;Essentia | Go to&nbsp;<a href="https://myessentia.com/dave" rel="noopener noreferrer" target="_blank">https://myessentia.com/dave</a>&nbsp;and use code DAVE for $100 off The Dave Asprey Upgrade.&nbsp;-&nbsp;iRestore&nbsp;| Reverse hair loss at&nbsp;<a href="http://www.irestore.com/DAVE" rel="noopener noreferrer" target="_blank">www.irestore.com/DAVE</a>&nbsp;and get exclusive savings on the&nbsp;iRestore&nbsp;Elite, use code DAVE&nbsp;&nbsp;Resources:&nbsp;&nbsp;&nbsp;• Get My 2026 Clean Nicotine Roadmap | Enroll for free at&nbsp;<a href="https://daveasprey.com/2026-clean-nicotine-roadmap/" rel="noopener noreferrer" target="_blank">https://daveasprey.com/2026-clean-nicotine-roadmap/</a>&nbsp;• Get My 2026 Biohacking Trends Report:&nbsp;<a href="https://daveasprey.com/2026-biohacking-trends-report/" rel="noopener noreferrer" target="_blank">https://daveasprey.com/2026-biohacking-trends-report/</a>&nbsp;• Dave Asprey's Latest News | Go to&nbsp;<a href="https://daveasprey.com/" rel="noopener noreferrer" target="_blank">https://daveasprey.com/</a>&nbsp;to&nbsp;join&nbsp;Inside Track&nbsp;today.&nbsp;&nbsp;• Danger Coffee:&nbsp;<a href="https://dangercoffee.com/discount/dave15" rel="noopener noreferrer" target="_blank">https://dangercoffee.com/discount/dave15</a>&nbsp;&nbsp;&nbsp;• My Daily Supplements:&nbsp;<a href="https://www.shopsuppgradelabs.com/discount/DAVE15" rel="noopener noreferrer" target="_blank">SuppGrade Labs</a>&nbsp;(15% Off)&nbsp;&nbsp;&nbsp;• Favorite Blue Light Blocking Glasses:&nbsp;<a href="https://truedark.com/?coupon-code=DAVEASPREY15&sc-page=shop" rel="noopener noreferrer" target="_blank">TrueDark</a>&nbsp;(15% Off)&nbsp;&nbsp;&nbsp;• Dave Asprey’s BEYOND Conference:&nbsp;<a href="https://beyondconference.com/" rel="noopener noreferrer" target="_blank">https://beyondconference.com</a>&nbsp;&nbsp;&nbsp;• Dave Asprey’s New Book –&nbsp;Heavily Meditated:&nbsp;<a href="https://daveasprey.com/heavily-meditated" rel="noopener noreferrer" target="_blank">https://daveasprey.com/heavily-meditated</a>&nbsp;&nbsp;• Join My Substack (Live Access&nbsp;To&nbsp;Podcast Recordings):&nbsp;<a href="https://substack.daveasprey.com/" rel="noopener noreferrer" target="_blank">https://substack.daveasprey.com/</a>&nbsp;• Upgrade Labs:&nbsp;<a href="https://upgradelabs.com/" rel="noopener noreferrer" target="_blank">https://upgradelabs.com</a>&nbsp;&nbsp;&nbsp;&nbsp;Timestamps:&nbsp;00:00 – Intro&nbsp;00:42 – Pancreatic Cancer Halted by Virus Injection&nbsp;01:44 – Teens & AI Therapy Chatbots&nbsp;03:13 – GLP-1 Drugs Cut Breast Cancer Risk&nbsp;04:30 – Russia's $26B Longevity Program&nbsp;06:18 – Sauna vs. Cold Plunge&nbsp;09:10 – Closing&nbsp;See Privacy Policy at <a href="https://art19.com/privacy" rel="noopener noreferrer" target="_blank">https://art19.com/privacy</a> and California Privacy Notice at <a href="https://art19.com/privacy#do-not-sell-my-info" rel="noopener noreferrer" target="_blank">https://art19.com/privacy#do-not-sell-my-info</a>.

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