The ceasefire between the U.S. and Iran expires soon as President Trump calls an extension highly unlikely and Vice President JD Vance heads to Pakistan for talks Iran won't publicly confirm it will attend.Labor Secretary Lori Chavez-DeRemer resigned amid allegations of an affair with her bodyguard, drinking on the job, and using taxpayer money for personal travel, becoming the third cabinet member to leave in less than two months.And President Trump's pick to lead the Federal Reserve faces his confirmation hearing today, but Republican Senator Thom Tillis is threatening to block it until the Justice Department drops its investigation of current Fed Chair Jerome Powell.A previous version of the story "Iran Ceasefire Deadline" incorrectly said the ceasefire between the US, Iran and Israel expires today. It expires on Wednesday. Want more analysis of the most important news of the day, plus a little fun? <a href="https://www.npr.org/newsletter/news"target="_blank" >Subscribe</a> to the Up First newsletter.Today’s episode of Up First was edited by Ruth Sherlock, Emily Kopp, Rafael Nam, Mohamad ElBardicy, and HJ Mai. It was produced by Ziad Buchh and Nia Dumas. Our director is Christopher Thomas. We get engineering support from Neisha Heinis. Our technical director is Carleigh Strange. And our Supervising Senior Producer is Vince Pearson. (0:00) Introduction(01:58) Iran Ceasefire Deadline(05:59) Labor Secretary Out(09:33) Hearing For New Fed Chair See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use of personal data for sponsorship and to manage your podcast sponsorship preferences. <a href="https://www.npr.org/about-npr/179878450/privacy-policy">NPR Privacy Policy</a>

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