This week, OpenAI announced a loosened partnership with Microsoft and an aggressive new strategy to secure computing power. We unpack what these updates signal about OpenAI’s business strategy and whether the company can scale while balancing a trial against Elon Musk and investor concerns over missed financial targets. Then, the A.I. researcher Dr. Adam Rodman, of Harvard Medical School, returns to tell us about the most significant ways A.I. is changing how doctors treat patients. And finally, can an LLM trained only on very old texts predict the future? We’re talking with one of the creators of the chatbot talkie.
 
Guests:
<ul>
 <li><a href="https://research.bidmc.org/general-medicine/people/adam-rodman-md-mph-facp" rel="noopener noreferrer">Dr. Adam Rodman</a>, internal medicine physician at Beth Israel Deaconess Medical Center and assistant professor at Harvard Medical School.</li>
 <li><a href="https://www.cs.toronto.edu/~duvenaud/" rel="noopener noreferrer">David Duvenaud</a>, associate professor at the University of Toronto, former team lead at Anthropic and co-creator of<a href="https://talkie-lm.com/introducing-talkie" rel="noopener noreferrer"> talkie</a>.</li>
</ul>
 
Additional Reading:
<ul>
 <li><a href="https://www.nytimes.com/2026/04/27/technology/microsoft-openai-partnership.html" rel="noopener noreferrer">Microsoft and OpenAI Loosen Their Partnership</a></li>
 <li><a href="https://www.nytimes.com/2026/04/23/technology/elon-musk-sam-altman-openai-trial.html" rel="noopener noreferrer">Elon Musk and Sam Altman’s Epic Fight Heads to Court</a></li>
 <li><a href="https://www.wsj.com/tech/ai/openai-misses-key-revenue-user-targets-in-high-stakes-sprint-toward-ipo-94a95273" rel="noopener noreferrer">OpenAI Misses Key Revenue, User Targets in High-Stakes Sprint Toward IPO</a></li>
 <li><a href="https://www.nytimes.com/2026/02/17/opinion/doctors-patients-ai.html" rel="noopener noreferrer">Take It From a Doctor: It’s OK if Your Medical Advice Comes From A.I.</a></li>
</ul>
 
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