The FIT Collective Genetic Insights Series – Episode 1Understanding Genetics, Stress & Weight with Dr. Ali NovitskyDr. Ali Novitsky, board-certified in obesity medicine, kicks off a new series on how genetics influence health—especially stress responses and weight regulation. She opens with a personal story: during college, despite eating well and exercising, she gained 20 pounds in three months. Genetic testing later revealed a variant in her cortisol receptor gene, causing her body to release excess cortisol under stress—leading to high blood sugar, insulin resistance, and ultimately, weight gain.Cortisol plays a central role in stress response and metabolism. While helpful in short bursts, chronic elevation from ongoing stress can disrupt insulin function, making weight loss more difficult for those with specific genetic variants. For Dr. Novitsky, managing stress—not restricting calories or increasing workouts—was the key to reversing her weight gain.About 30% of people carry this cortisol receptor variant. In her 2022 genetics cohort, 80% tested positive. This highlights the power of personalized health strategies rooted in understanding one’s unique genetic makeup.Dr. Novitsky uses Genomind’s Mental Health Map, a genetic test offering insight into stress, mood, and focus. One critical gene it reports on is COMT, which affects dopamine breakdown. Individuals with the MetMet variant retain more dopamine—great for focus, but often sensitive to stress. Those with ValVal clear dopamine quickly, leading to impulsivity and a higher likelihood of ADHD.Another important factor is BDNF (brain-derived neurotrophic factor), a gene linked to memory, cognition, and mood. Those with a BDNF variant often need regular exercise to optimize brain health and emotional balance.The takeaway? Health isn’t one-size-fits-all. For some, gentle exercise, high-quality sleep, and stress reduction may be far more effective than intense workouts or calorie restriction. Dr. Novitsky’s approach integrates genetic awareness into actionable wellness strategies.She also introduces her four-week genetics program, which includes one-time testing, personalized supplement recommendations, and coaching based on individual results. Participants receive a lifelong health blueprint.Future episodes will explore the genetics of eating behaviors, including cravings and satiety. Listeners are encouraged to tune in and learn how DNA influences decisions, habits, and long-term health.Timestamps00:00:00 - Introduction and Personal Story00:01:00 - Understanding Cortisol and Stress00:04:00 - Genetic Testing Insights00:05:30 - Cortisol and Weight Management00:08:00 - COMT Variants and Dopamine00:10:00 - Dopamine Receptor Genes00:11:00 - Strategies for Managing Genetics00:12:00 - Genetics Program Announcement00:13:00 - Custom Recommendations Based on Genetics00:15:00 - The Role of Serotonin and Oxytocin00:16:00 - Genetic Influences on Eating Behaviors00:18:00 - Stress Response and Emotional Eating00:20:00 - The Importance of Awareness00:22:00 - BDNF and Exercise00:23:00 - Micro-Dosed Lithium and Mood00:24:00 - Genetic Predispositions to Worry00:25:00 - Empowerment Through Genetic Awareness00:26:00 - Preview of Next Episode on Eating Genetics00:27:00 - Enrollment for Genetics Program00:28:00 - Closing RemarksWork with Dr. Ali• Beginner Strength Training Program – 12 months for only $199! ⁠⁠⁠⁠⁠<a href="https://www.trainerize.me/profile/thefitcollectiveapp/?planGUID=8b488ef7255547cbadab2fe9bf5bf0c2&mode=checkout">⁠Enroll TODAY⁠</a>⁠⁠⁠⁠⁠• Total Fitness Program – A 12-month mind-body experience. ⁠⁠⁠⁠⁠<a href="https://www.trainerize.me/profile/thefitcollectiveapp/?planGUID=fb07cea512af4b05b30dd11c2e827255&mode=checkout">⁠Enroll HERE⁠⁠⁠⁠⁠⁠</a>• The Fit Collective® x InBody USA/Canada – Get 15% off select models. <a href="#">⁠⁠⁠⁠⁠⁠Click HERE⁠</a>

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