Scientists are tuning in to a surprising conversation happening inside us—between our gut and our brain. Host Rachel Feltman chats with Maya Kaelberer, an assistant professor at the University of Arizona’s department of physiology, to explore how intestinal cells and microbiomes might be shaping our moods, cravings and mental health in ways we’re only beginning to understand.

Recommended Reading
<a href="https://www.nature.com/articles/s41586-025-09301-7">“A Gut Sense for a Microbial Pattern Regulates Feeding,” by Winston W. Liu et al., in Nature. Published online July 23, 2025</a>
<a href="https://www.gutbrainlaboratory.org/">Website for the Gut Brain Laboratory at the University of Arizona</a>
<a href="https://thinkgastronauts.com">The gut-brain community website Gastronauts</a>

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Science Quickly is produced by Rachel Feltman, Fonda Mwangi and Jeff DelViscio. This episode was edited by Alex Sugiura. Shayna Posses and Aaron Shattuck fact-check the show. The theme music was composed by Dominic Smith.
This episode was made possible by the support of <a href="https://www.yakult.co.jp/english/">Yakult</a> and produced independently by Scientific American’s board of editors. Learn more about your ad choices. Visit <a href="https://megaphone.fm/adchoices">megaphone.fm/adchoices</a>

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The Role Our Microbiome Plays In Our ‘Gut Feelings’

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