In this episode:<h2>00:45 Implanted brain organoids could offer new insights into disease</h2>Brain organoids — lab-grown, self-organizing structures made of stem cells — are used in research to better understand brain development and disease progression. However, these structures lack connections seen in real brains, limiting their usefulness. To overcome this, a team has now transplanted human organoids into the brains of newborn rats, showing that these implanted organoids respond to stimuli and could influence the animals’ behaviour.Research article: <a href="https://www.nature.com/articles/s41586-022-05277-w?utm_source=naturepod&utm_medium=podcast&utm_campaign=shownotes" rel="noopener noreferrer" target="_blank">Revah et al.</a>News and Views: <a href="https://www.nature.com/articlesd41586-022-02977-1?utm_source=naturepod&utm_medium=podcast&utm_campaign=shownotes" rel="noopener noreferrer" target="_blank">Human brain organoids influence rat behaviour</a><h2>09:20 Research Highlights</h2>The subtle timing shift that gives jazz music its ‘swing’, and why hydrogen power could be a cost-effective way to reduce heavy industry emissions in China. Research Highlight: <a href="https://www.nature.com/articles/d41586-022-03082-z?utm_source=naturepod&utm_medium=podcast&utm_campaign=shownotes" rel="noopener noreferrer" target="_blank">What gives jazz its swing? A delay makes the difference</a>Research Highlight: <a href="https://www.nature.com/articles/d41586-022-03084-x?utm_source=naturepod&utm_medium=podcast&utm_campaign=shownotes" rel="noopener noreferrer" target="_blank">Hydrogen could help China’s heavy industry to get greener</a><h2>11:46 The exoskeleton boot that makes walking more efficient</h2>Wearable robotic exoskeletons that aid or enhance movement are fast becoming a reality, but there are challenges to overcome — to work best these devices frequently require careful calibration for their user using specialist equipment and time in a lab. Now, a team have created exoskeleton boots that can help people walk faster and more efficiently by learning and adapting to the wearer’s gait as they walk. They hope that this approach could be used to develop personalised assistive devices in the future.Research article: <a href="https://www.nature.com/articles/s41586-022-05191-1?utm_source=naturepod&utm_medium=podcast&utm_campaign=shownotes" rel="noopener noreferrer" target="_blank">Slade et al.</a>Nature Video: <a href="https://www.youtube.com/watch?v=989EIeMXQfo?utm_source=naturepod&utm_medium=podcast&utm_campaign=shownotes" rel="noopener noreferrer" target="_blank">The robot boot that learns as you walk</a><a href="https://go.nature.com/get-the-nature-briefing" rel="noopener noreferrer" target="_blank">Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.</a><hr> Hosted on Acast. See <a style='color:grey;' target='_blank' rel='noopener noreferrer' href='https://acast.com/privacy'>acast.com/privacy</a> for more information.

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Human brain organoids implanted into rats could offer new way to model disease

Nature Podcast