Huberman Lab

<br/><br/><h4>Podcast Notes <strong>Key Takeaways</strong></h4> <ul><li>Neural circuits (not individual brain areas) trigger aggression</li><li>Aggression is not a switch, it’s a process with a beginning, middle, and end</li><li>Aggression actually hinges on the hormone estrogen</li><li>Testosterone in and of itself does not trigger aggression – testosterone aromatized into estrogen within the brain and binding to estrogen receptors in area of the brain that leads to aggression</li><li>Estrogen triggers aggression in brain and testosterone increases the pressure toward an aggressive episode</li><li>Recipe for aggression & reactivity: increased cortisol, reduced serotonin, short days</li><li>Self-regulation is a key component of whether someone will engage in aggressive behavior</li><li>Tools to reduce aggressive tendencies and impulsivity: pay attention to how daylight changes makes you feel, supplement with omega-3, supplement with ashwagandha in 2 week on/2week off cycles, get sunlight early in the day, try a hot bath or sauna, avoid beverages that contain both alcohol and caffeine</li></ul><a href="https://podcastnotes.org/huberman-lab/episode-71-understanding-controlling-aggression-huberman-lab/">Read the full notes @ podcastnotes.org</a><hr><p>This episode I describe the neural mechanisms that activate and control aggressive states and beahviors and the role of hormones—estrogen and testosterone—in mediating violent and and/or competive aggression. I also describe tools that can be used to modulate the factors that have been shown to ‘prime’ an individual for aggression, including sunlight, estrogen sensitivity, competition within social settings, and overall stress levels, and the hormone cortisol. I discuss how substances such as caffeine and alcohol can impact impulsive behaviors, and how nutrition and supplementation can be used to regulate mood and aggression. 
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For the full show notes, visit hubermanlab.com.
Timestamps
(00:00:00) Aggression, Types of Aggression
(00:03:33) AG1 (Athletic Greens), ROKA, Helix Sleep
(00:08:29) Neural Circuits for Aggression, “Hydraulic Pressure Model” 
(00:15:50) Brain Regions Controlling Aggression, Ventromedial Hypothalamus (VMH) 
(00:22:14) Psychiatric Disorders &amp; Aggression 
(00:23:36) Stimulation of the VMH, Estrogen Receptors &amp; Aggression
(00:31:57) Neural Circuits Mediating Physical Acts of Aggression, Biting
(0:35:56) Testosterone &amp; Competitiveness/Estrogen &amp; Aggression 
(00:43:00) Sunlight, Melatonin &amp; Aggression 
(00:45:46) Cortisol, Serotonin &amp; Aggressive Behaviors 
(00:51:56) Tool: Omega-3 Supplementation &amp; Mood 
(00:54:18) Tool: Sunlight, Sauna &amp; Cortisol Reduction
(00:55:54) Tool: Ashwagandha &amp; Cortisol Reduction
(00:57:06) Tool: Seasonality/Sunlight, Genetic Variation in Estrogen Sensitivity
(01:00:37) Testosterone &amp; Aggression, Competitive Work Environments
(01:05:07) Testosterone, Amygdala, Challenge &amp; Effort 
(01:09:27) Caffeine, Alcohol &amp; Impulsivity 
(01:13:15) Tool: Caffeinated Alcohol Beverages, Impulsivity &amp; Aggression 
(01:17:18) Tool: ADHD, Acetyl-L Carnitine &amp; Aggressive Behavior 
(01:24:10) Factors Affecting the “Hydraulic Pressure Model” of Aggression 
(01:25:44) Book by Dr. David Anderson, Aggression &amp; Social Relationships 
(01:27:35) Zero-Cost Support, YouTube Feedback, Spotify &amp; Apple Reviews, Sponsors, Patreon, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter
Title Card Photo Credit: Mike Blabac
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Understanding & Controlling Aggression | Episode 71

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